Synthesis of PVP-coated ultra-small Fe3O4 nanoparticles as a MRI contrast agent

doi:10.1007/s10856-009-3881-3

IMR OpenIR

	Synthesis of PVP-coated ultra-small Fe3O4 nanoparticles as a MRI contrast agent
	Zhang, Ying 1,2,3; Liu, Jing-Ying 3; Ma, Song 1,2; Zhang, Ya-Jing 1,2; Zhao, Xiang 3; Zhang, Xiang-Dong 1,2,4; Zhang, Zhi-Dong 1,2
通讯作者	Zhang, Ying(yzhang7704@imr.ac.cn)
	2010-04-01
发表期刊	JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
ISSN	0957-4530
卷号	21 期号:4 页码:1205-1210
摘要	Ultra-small Fe3O4 nanoparticles were prepared by using the coprecipitation method, in which the polyvinylpyrrolidone (PVP) serves as a stabilizer. The nanoparticles were characterized by means of X-ray diffraction (XRD), transmission electron microscopy (TEM), infra spectrum (IR), X-ray photoelectron spectroscopy (XPS) and in vivo magnetic resonance imaging (MRI) test. The results showed that the particles' size was determined by the dripping rate and that PVP molecules played the role of preventing the aggregation and restricting the size of Fe3O4 nanoparticles. The Fe3O4 nanoparticles with diameter from 6.5 to 1.9 nm obviously exhibited negative contrast enhancement and concentrated at the target area guided by a permanent magnet.
资助者	National Natural Science Foundation of China
DOI	10.1007/s10856-009-3881-3
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[50331030] ; National Natural Science Foundation of China[50831006]
WOS研究方向	Engineering ; Materials Science
WOS类目	Engineering, Biomedical ; Materials Science, Biomaterials
WOS记录号	WOS:000276275600019
出版者	SPRINGER
引用统计	被引频次：86[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/101225
专题	中国科学院金属研究所
通讯作者	Zhang, Ying
作者单位	1.Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Int Ctr Mat Phys, Shenyang 110016, Peoples R China 3.Shen Yang Pharmaceut Univ, Coll Pharmaceut Engn, Shenyang 110016, Peoples R China 4.Liaoning Univ, Coll Chem Sci & Engn, Shenyang 110036, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Ying,Liu, Jing-Ying,Ma, Song,et al. Synthesis of PVP-coated ultra-small Fe3O4 nanoparticles as a MRI contrast agent[J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,2010,21(4):1205-1210.
APA	Zhang, Ying.,Liu, Jing-Ying.,Ma, Song.,Zhang, Ya-Jing.,Zhao, Xiang.,...&Zhang, Zhi-Dong.(2010).Synthesis of PVP-coated ultra-small Fe3O4 nanoparticles as a MRI contrast agent.JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,21(4),1205-1210.
MLA	Zhang, Ying,et al."Synthesis of PVP-coated ultra-small Fe3O4 nanoparticles as a MRI contrast agent".JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 21.4(2010):1205-1210.