Recent Advances on Biodegradable MgYREZr Magnesium Alloy
Tan Lili1; Chen Junxiu1,2; Yu Xiaoming1; Yang Ke1
Corresponding AuthorTan Lili(
AbstractIn recent years, magnesium and its alloys as biodegradable materials have attracted much attention. Biodegradable MgYREZr, mainly WE43 alloy, with good integrated properties has been studied in favor. In this paper, the microstructure, mechanical properties, biodegradable property and biocompatibility of biodegradable MgYREZr alloy were reviewed, as well as the clinical results of the bone fixation screws developed in Germany using the alloy with similar composition to WE43. MgYREZr alloy presents uniform microstructure and higher mechanical properties after large plastic deformation with the grain size of less than 1 mm. The RE elements can be dissolved and stabilize the corrosion layer, which can decrease the degradation rate of the alloy accompanying with optimized heat treatment. The animal tests showed biocompatibility and good bioactivity. Clinical tests showed the MgYREZr alloy screws presented equivalent to titanium screws for the treatment of mild hallux valgus deformities, however resorption cysts was revealed by X-rays when the acute scaphoid fractures were treated with a double-threaded screw made of MgYREZr, and it was only after 6 months that the fractures were consolidated enough to allow physical work. So for different clinical cases, the degradation and biological behaviors of MgYREZr alloys need to be further studied in vitro and in vivo. To control the degradation rates to meet the different clinical requirements is still a major obstacle for biodegradable MgYREZr alloys to enlarge their clinical application.
KeywordMgYREZr alloy microstructure mechanical property biodegradable property biocompatibility
Funding OrganizationNational Natural Science Foundation of China
Indexed BySCI
Funding ProjectNational Natural Science Foundation of China[81401773] ; National Natural Science Foundation of China[31500777]
WOS Research AreaMetallurgy & Metallurgical Engineering
WOS SubjectMetallurgy & Metallurgical Engineering
WOS IDWOS:000416301400006
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Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorTan Lili
Affiliation1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China
2.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Liaoning, Peoples R China
Recommended Citation
GB/T 7714
Tan Lili,Chen Junxiu,Yu Xiaoming,et al. Recent Advances on Biodegradable MgYREZr Magnesium Alloy[J]. ACTA METALLURGICA SINICA,2017,53(10):1207-1214.
APA Tan Lili,Chen Junxiu,Yu Xiaoming,&Yang Ke.(2017).Recent Advances on Biodegradable MgYREZr Magnesium Alloy.ACTA METALLURGICA SINICA,53(10),1207-1214.
MLA Tan Lili,et al."Recent Advances on Biodegradable MgYREZr Magnesium Alloy".ACTA METALLURGICA SINICA 53.10(2017):1207-1214.
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