A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study

IMR OpenIR

	A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study
	Zhou, Xiaoshu 1; Zhu, Yue 1; Zhang, Xing 2; Yuan, Wei 1; Lu, Fatai 3; Tan, Yuelong 4
通讯作者	Zhu, Yue(zhuyuedr@163.com)
	2018
发表期刊	INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
ISSN	1940-5901
卷号	11 期号:3 页码:1908-+
摘要	Lumbar facet joint is the main motion unit of the spine in the posterior column. Improving facet fusion rate has been a subject of intense interest in the spine surgery field. Even though a number of implants like autogenous bone graft, facet screws, translaminar facet screw, allograft bone dowel have been proposed, the facet joint fusion rate varies from 10.14% to 97.3%, combined with multiple screw related complications. An experimental beagle dog lumbar facet fusion study was conducted to compare the fusion performance of a new lumbar facet cage filled with autogenous cancellous bone with that of autogenous bone block alone. A total of 12 beagle dogs were randomly divided into the facet cage group and the autogenous bone alone group. They all underwent L3-L5 lumbar facet joint fusion surgery with either facet cage filled with autogenous cancellous bone or autogenous bone block alone. Six months after the surgery, lumbar segment fusion state was analyzed with manual palpation, CT, micro-CT and histology method. And the bone fusion rate in the facet cage group was 87.5% compared with 41.6% in the autogenous bone block alone group (p< 0.05). Micro-CT and histology study further confirmed more bone formation in the facet cage group. In conclusion, the new lumbar facet cage could yield a satisfactory fusion rate, which was significantly higher than that of autogenous bone alone in the Beagle dog lumbar facet joint fusion model.
关键词	Facet joint fusion cage canine
资助者	Liaoning Science and Technology Project, China
收录类别	SCI
语种	英语
资助项目	Liaoning Science and Technology Project, China[2015225014]
WOS研究方向	Research & Experimental Medicine
WOS类目	Medicine, Research & Experimental
WOS记录号	WOS:000429006600055
出版者	E-CENTURY PUBLISHING CORP
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/127742
专题	中国科学院金属研究所
通讯作者	Zhu, Yue
作者单位	1.China Med Univ, Hosp 1, Dept Orthoped, 155 Nanjingbei St, Shenyang, Liaoning, Peoples R China 2.Chinese Acad Sci, Inst Met Res, 72 Wenhua St, Shenyang, Liaoning, Peoples R China 3.China Med Univ, Hosp 4, Dept Orthoped, 4 Chongshandong St, Shenyang, Liaoning, Peoples R China 4.Ansteel Grp Hosp, Dept Orthoped, 3 Jianshen St, Anshan City, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Xiaoshu,Zhu, Yue,Zhang, Xing,et al. A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2018,11(3):1908-+.
APA	Zhou, Xiaoshu,Zhu, Yue,Zhang, Xing,Yuan, Wei,Lu, Fatai,&Tan, Yuelong.(2018).A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,11(3),1908-+.
MLA	Zhou, Xiaoshu,et al."A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 11.3(2018):1908-+.