| A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study | |
| Zhou, Xiaoshu1; Zhu, Yue1; Zhang, Xing2; Yuan, Wei1; Lu, Fatai3; Tan, Yuelong4 | |
| Corresponding Author | Zhu, Yue(zhuyuedr@163.com) |
| 2018 | |
| Source Publication | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
 |
| ISSN | 1940-5901 |
| Volume | 11Issue:3Pages:1908-+ |
| Abstract | Lumbar facet joint is the main motion unit of the spine in the posterior column. Improving facet fusion rate has been a subject of intense interest in the spine surgery field. Even though a number of implants like autogenous bone graft, facet screws, translaminar facet screw, allograft bone dowel have been proposed, the facet joint fusion rate varies from 10.14% to 97.3%, combined with multiple screw related complications. An experimental beagle dog lumbar facet fusion study was conducted to compare the fusion performance of a new lumbar facet cage filled with autogenous cancellous bone with that of autogenous bone block alone. A total of 12 beagle dogs were randomly divided into the facet cage group and the autogenous bone alone group. They all underwent L3-L5 lumbar facet joint fusion surgery with either facet cage filled with autogenous cancellous bone or autogenous bone block alone. Six months after the surgery, lumbar segment fusion state was analyzed with manual palpation, CT, micro-CT and histology method. And the bone fusion rate in the facet cage group was 87.5% compared with 41.6% in the autogenous bone block alone group (p< 0.05). Micro-CT and histology study further confirmed more bone formation in the facet cage group. In conclusion, the new lumbar facet cage could yield a satisfactory fusion rate, which was significantly higher than that of autogenous bone alone in the Beagle dog lumbar facet joint fusion model. |
| Keyword | Facet joint fusion cage canine |
| Funding Organization | Liaoning Science and Technology Project, China |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Liaoning Science and Technology Project, China[2015225014] |
| WOS Research Area | Research & Experimental Medicine |
| WOS Subject | Medicine, Research & Experimental |
| WOS ID | WOS:000429006600055 |
| Publisher | E-CENTURY PUBLISHING CORP |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/127742 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Zhu, Yue |
| Affiliation | 1.China Med Univ, Hosp 1, Dept Orthoped, 155 Nanjingbei St, Shenyang, Liaoning, Peoples R China 2.Chinese Acad Sci, Inst Met Res, 72 Wenhua St, Shenyang, Liaoning, Peoples R China 3.China Med Univ, Hosp 4, Dept Orthoped, 4 Chongshandong St, Shenyang, Liaoning, Peoples R China 4.Ansteel Grp Hosp, Dept Orthoped, 3 Jianshen St, Anshan City, Liaoning, Peoples R China |
| Recommended Citation GB/T 7714 | Zhou, Xiaoshu,Zhu, Yue,Zhang, Xing,et al. A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2018,11(3):1908-+. |
| APA | Zhou, Xiaoshu,Zhu, Yue,Zhang, Xing,Yuan, Wei,Lu, Fatai,&Tan, Yuelong.(2018).A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,11(3),1908-+. |
| MLA | Zhou, Xiaoshu,et al."A new lumbar facet cage to enhance facet joint fusion: an experimental beagle study".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 11.3(2018):1908-+. |
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