| Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate | |
| Yu Xiaoming1; Tan Lili1; Liu Zongyuan1; Yang Ke1; Zhu Zhonglin2; Li Yangde3 | |
| Corresponding Author | Tan Lili(lltan@imr.ac.cn) |
| 2018-06-01 | |
| Source Publication | ACTA METALLURGICA SINICA
 |
| ISSN | 0412-1961 |
| Volume | 54Issue:6Pages:943-949 |
| Abstract | Currently, metallic biomaterials used in orthopedics are normally bioinert which is hard to integrate with the bone tissue inducing aseptic loosening and easy to get infection, which is the main reason of implantation failure. Mg base metals are considered to be a new generation of revolutionary metallic biomaterials due to its similar density and mechanical properties with natural bone, good biocompatibility, degradability in the body as well as the biological functional ability to promote new bone tissue formation. In addition, the degradation of Mg may increase the local pH which can inhibit the growth of bacteria. In this work, pure Mg coating was deposited on Ti6Al4V substrate by arc ion plating. The effects of different working pressures on the surface quality and properties of Mg coating were investigated. The degradation, antibacterial and biosafety properties were studyied. The results showed that the pure Mg coating can be deposited on the surface of Ti6Al4V substrate and the coating was uniform and smooth. The immersion test in vitro showed that the degradation was very fast because of galvanic corrosion, and the whole process was finished in about one week. The results of antimicrobial experiments showed that the Mg coating can kill staphylococcus aureus and showed good antibacterial function. The results of cytotoxicity test showed that Mg coating promoted rabbit bone marrow mesenchymal stem cells (rBMSCs) growth and proliferation. |
| Keyword | Ti alloy pure Mg coating bioproperty |
| Funding Organization | National Natural Science Foundation of China ; National Key Research and Development Program of China |
| DOI | 10.11900/0412.1961.2017.00285 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[81500897] ; National Natural Science Foundation of China[81400528] ; National Key Research and Development Program of China[2016YFC1101804] |
| WOS Research Area | Metallurgy & Metallurgical Engineering |
| WOS Subject | Metallurgy & Metallurgical Engineering |
| WOS ID | WOS:000433007400014 |
| Publisher | SCIENCE PRESS |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/128469 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Tan Lili |
| Affiliation | 1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Jiangsu OKANI Med Technol Co Ltd, Suzhou 215123, Peoples R China 3.Dong Guan EONTC Co Ltd, Dongguan 523808, Peoples R China |
| Recommended Citation GB/T 7714 | Yu Xiaoming,Tan Lili,Liu Zongyuan,et al. Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate[J]. ACTA METALLURGICA SINICA,2018,54(6):943-949. |
| APA | Yu Xiaoming,Tan Lili,Liu Zongyuan,Yang Ke,Zhu Zhonglin,&Li Yangde.(2018).Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate.ACTA METALLURGICA SINICA,54(6),943-949. |
| MLA | Yu Xiaoming,et al."Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate".ACTA METALLURGICA SINICA 54.6(2018):943-949. |
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