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Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate
Yu Xiaoming1; Tan Lili1; Liu Zongyuan1; Yang Ke1; Zhu Zhonglin2; Li Yangde3
Corresponding AuthorTan Lili(lltan@imr.ac.cn)
2018-06-01
Source PublicationACTA METALLURGICA SINICA
ISSN0412-1961
Volume54Issue:6Pages:943-949
AbstractCurrently, metallic biomaterials used in orthopedics are normally bioinert which is hard to integrate with the bone tissue inducing aseptic loosening and easy to get infection, which is the main reason of implantation failure. Mg base metals are considered to be a new generation of revolutionary metallic biomaterials due to its similar density and mechanical properties with natural bone, good biocompatibility, degradability in the body as well as the biological functional ability to promote new bone tissue formation. In addition, the degradation of Mg may increase the local pH which can inhibit the growth of bacteria. In this work, pure Mg coating was deposited on Ti6Al4V substrate by arc ion plating. The effects of different working pressures on the surface quality and properties of Mg coating were investigated. The degradation, antibacterial and biosafety properties were studyied. The results showed that the pure Mg coating can be deposited on the surface of Ti6Al4V substrate and the coating was uniform and smooth. The immersion test in vitro showed that the degradation was very fast because of galvanic corrosion, and the whole process was finished in about one week. The results of antimicrobial experiments showed that the Mg coating can kill staphylococcus aureus and showed good antibacterial function. The results of cytotoxicity test showed that Mg coating promoted rabbit bone marrow mesenchymal stem cells (rBMSCs) growth and proliferation.
KeywordTi alloy pure Mg coating bioproperty
Funding OrganizationNational Natural Science Foundation of China ; National Key Research and Development Program of China
DOI10.11900/0412.1961.2017.00285
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[81500897] ; National Natural Science Foundation of China[81400528] ; National Key Research and Development Program of China[2016YFC1101804]
WOS Research AreaMetallurgy & Metallurgical Engineering
WOS SubjectMetallurgy & Metallurgical Engineering
WOS IDWOS:000433007400014
PublisherSCIENCE PRESS
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/128469
Collection中国科学院金属研究所
Corresponding AuthorTan Lili
Affiliation1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China
2.Jiangsu OKANI Med Technol Co Ltd, Suzhou 215123, Peoples R China
3.Dong Guan EONTC Co Ltd, Dongguan 523808, Peoples R China
Recommended Citation
GB/T 7714
Yu Xiaoming,Tan Lili,Liu Zongyuan,et al. Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate[J]. ACTA METALLURGICA SINICA,2018,54(6):943-949.
APA Yu Xiaoming,Tan Lili,Liu Zongyuan,Yang Ke,Zhu Zhonglin,&Li Yangde.(2018).Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate.ACTA METALLURGICA SINICA,54(6),943-949.
MLA Yu Xiaoming,et al."Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate".ACTA METALLURGICA SINICA 54.6(2018):943-949.
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