Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants

doi:10.1016/j.jmst.2018.10.020

IMR OpenIR

	Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants
	Cao, Lei 1,2; Ullah, Ihsan 1,3; Li, Na 1; Niu, Shiyu 4; Sun, Rujie 5; Xia, Dandan 4; Yang, Rui 1,3; Zhang, Xing 1,3
通讯作者	Zhang, Xing(xingzhang@imr.ac.cn)
	2019-05-01
发表期刊	JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN	1005-0302
卷号	35 期号:5 页码:719-726
摘要	Plasma-sprayed hydroxyapatite (HA) coatings have been widely utilized in load-bearing titanium alloy implants. In this study, Mg, Sr co-substituted HA ((Mg, Sr)-HA) nano-scale powders have been synthesized, which are further used to prepare (Mg, Sr)-HA coatings on Ti-6Al-4V alloys in order to improve the biological functions. The average size of (Mg, Sr)-HA nano particles is similar to 75 nm. The average bonding strength for (Mg, Sr)-HA coating and samples after heat treatment at 500 degrees C or 600 degrees C for 3h are 26.17 +/- 2.11 MPa, 36.07 +/- 4.48 MPa and 37.07 +/- 2.95 MPa, respectively. There is a significantly increase of bonding strength likely due to low residual stress after heated treatment. MC3T3-E1 cells show a high proliferation rate when cultured with (Mg, Sr)-HA coating extract compared to the normal culture medium, which also exhibit large extension and deposition of extracellular matrices when adhered on the coating surfaces. Thus, these (Mg, Sr)-HA coatings show high bonding strength and improved biological functions, which offer promising future applications in the fields of orthopedics and dentistry. (C) 2019 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
关键词	Plasma spray Hydroxyapatite Titanium alloys Biological functions Bonding strength
资助者	National Key Research and Development Program of China from Ministry of Science and Technology ; College Students' Innovative Program of Liaoning Province ; Key Research Program of Frontier Sciences ; Hundred Talent Program from Chinese Academy of Sciences (CAS) ; Innovation Research Program from Institute of Metal Research, CAS
DOI	10.1016/j.jmst.2018.10.020
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China from Ministry of Science and Technology[2016YFC1100502] ; College Students' Innovative Program of Liaoning Province[201310163023] ; Key Research Program of Frontier Sciences[QYZDY-SSW-JSC027] ; Hundred Talent Program from Chinese Academy of Sciences (CAS) ; Innovation Research Program from Institute of Metal Research, CAS[2015-ZD01]
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
WOS类目	Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS记录号	WOS:000460640200003
出版者	JOURNAL MATER SCI TECHNOL
引用统计	被引频次：53[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/132403
专题	中国科学院金属研究所
通讯作者	Zhang, Xing
作者单位	1.Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 239056, Anhui, Peoples R China 4.Shenyang Pharmaceut Univ, Shenyang 110016, Liaoning, Peoples R China 5.Univ Utah, Salt Lake City, UT 84112 USA
推荐引用方式 GB/T 7714	Cao, Lei,Ullah, Ihsan,Li, Na,et al. Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2019,35(5):719-726.
APA	Cao, Lei.,Ullah, Ihsan.,Li, Na.,Niu, Shiyu.,Sun, Rujie.,...&Zhang, Xing.(2019).Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,35(5),719-726.
MLA	Cao, Lei,et al."Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 35.5(2019):719-726.