IMR OpenIR
Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study
Peng, Wei1,2; Chen, Jun-Xiu3,4; Shan, Xian-Feng2; Wang, Yi-Chuan2; He, Fan2; Wang, Xue-Jin1; Tan, Li-Li3; Yang, Ke3
Corresponding AuthorWang, Xue-Jin(wxj0411@aliyun.com) ; Tan, Li-Li(lltan@imr.ac.cn)
2019-06-01
Source PublicationRARE METALS
ISSN1001-0521
Volume38Issue:6Pages:577-587
AbstractA novel calcium-phosphate (Ca-P)-coated magnesium (Mg) membrane used for guided bone regeneration (GBR) was studied. The microstructural characterization, electrochemical test, immersion test, fluorescence labeling analysis and histopathological evaluation were carried out. The results showed that Ca-P coating could obviously improve the corrosion resistance of the pure Mg membrane. The in vivo results showed that Mg membrane coated with Ca-P would take 8weeks to be completely absorbed. However, Mg membrane was completely absorbed within 1week. Histopathological evaluation showed that the Ca-P-coated Mg membranes were significantly better than Ti membranes at the early implantation time (4weeks), and with the time prolonging, the performance of the coated Mg membrane was not as good as pure Ti membranes (but still better than blank group) at 8 and 12weeks. The coated biodegradable Mg membrane had a good promising application in GBR. But further studies have to be done to further decrease the degradation rate of pure Mg membrane.
KeywordBone defect Guided bone regeneration Ca-P-coated magnesium (Mg) membrane Bioabsorbable membrane
Funding OrganizationKey Program of China on Biomedical Materials Research and Tissue and Organ Replacement ; Shenyang Key R&D and Technology Transfer Program
DOI10.1007/s12598-019-01273-8
Indexed BySCI
Language英语
Funding ProjectKey Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1101804] ; Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1100604] ; Shenyang Key R&D and Technology Transfer Program[Z18-0-027]
WOS Research AreaMaterials Science ; Metallurgy & Metallurgical Engineering
WOS SubjectMaterials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS IDWOS:000469800600012
PublisherNONFERROUS METALS SOC CHINA
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/133812
Collection中国科学院金属研究所
Corresponding AuthorWang, Xue-Jin; Tan, Li-Li
Affiliation1.Dalian Univ, Dept Stomatol, Zhongshan Hosp, Dalian 116001, Peoples R China
2.Dalian Univ, Sch Med, Dalian 116622, Peoples R China
3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China
4.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Liaoning, Peoples R China
Recommended Citation
GB/T 7714
Peng, Wei,Chen, Jun-Xiu,Shan, Xian-Feng,et al. Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study[J]. RARE METALS,2019,38(6):577-587.
APA Peng, Wei.,Chen, Jun-Xiu.,Shan, Xian-Feng.,Wang, Yi-Chuan.,He, Fan.,...&Yang, Ke.(2019).Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study.RARE METALS,38(6),577-587.
MLA Peng, Wei,et al."Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study".RARE METALS 38.6(2019):577-587.
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