Biomechanical compatibility of high strength nickel free stainless steel bone plate under lightweight design

doi:10.1016/j.msec.2019.03.082

IMR OpenIR

	Biomechanical compatibility of high strength nickel free stainless steel bone plate under lightweight design
	Ren, Yibin 1; Zhao, Haochuan 2; Yang, Ke 3; Zhang, Yu 4
通讯作者	Ren, Yibin(yb.ren@163.com)
	2019-08-01
发表期刊	MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
ISSN	0928-4931
卷号	101 页码:415-422
摘要	High nitrogen nickel-free stainless steel (HNNFSS) has excellent mechanical properties, corrosion resistance and biocompatibility, but its strength advantage is not fully used even though with one time higher than that of the conventional 316 L stainless steel. In this work, the lightweight design of HNNFSS bone plate was studied using finite element analysis, and the effect of lightweight plate fixation on histological and biomechanical behavior of healing bone were also researched on fractured rabbit femur. The finite element analysis results showed that the lightweight plate within 18.2% thickness reduction had higher bending strength and more homogeneous stress distribution compared with 316 L stainless steel plate. There was no obvious difference in radiography, histology analysis of callus and expression pattern of insulin like growth factor-1(IGF-1) of callus between the lightweight HNNFSS plate group and 316 L stainless steel plate group in animal test, and the IGF-1 concentrations of callus and the biomechanical bending test results also showed no statistical significance (p > 0.05), even though the data of the lightweight HNNFSS plate group were relatively better than that of 316 L stainless steel plate group. Therefore, the high nitrogen nickel-free stainless steel has the lightweight potential to keep good fixing function and improve bone healing compared with 316 L stainless steel plate.
关键词	Lightweight High nitrogen stainless steel Biomechanical Stress shielding Biocompatibility
资助者	Natural Science Foundation of China
DOI	10.1016/j.msec.2019.03.082
收录类别	SCI
语种	英语
资助项目	Natural Science Foundation of China[31370976]
WOS研究方向	Materials Science
WOS类目	Materials Science, Biomaterials
WOS记录号	WOS:000471359100040
出版者	ELSEVIER SCIENCE BV
引用统计	被引频次：12[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/133898
专题	中国科学院金属研究所
通讯作者	Ren, Yibin
作者单位	1.Shenyang Ligong Univ, Sch Mat Sci & Engn, Shenyang 110159, Liaoning, Peoples R China 2.AECC Guizhou Liyang Aviat Power Co LTD, Guiyang 550014, Guizhou, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 4.PLA South Mil Command Reg Gen Hosp, Hosp Orthoped, Guangzhou 510010, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Ren, Yibin,Zhao, Haochuan,Yang, Ke,et al. Biomechanical compatibility of high strength nickel free stainless steel bone plate under lightweight design[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2019,101:415-422.
APA	Ren, Yibin,Zhao, Haochuan,Yang, Ke,&Zhang, Yu.(2019).Biomechanical compatibility of high strength nickel free stainless steel bone plate under lightweight design.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,101,415-422.
MLA	Ren, Yibin,et al."Biomechanical compatibility of high strength nickel free stainless steel bone plate under lightweight design".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 101(2019):415-422.