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Study of TiCu/TiCuN multilayer films with antibacterial activity
Wang, Jingren1; Zhao, Bing1; Li, Gaiming2; Yang, Ke3; Yu, Jiaying1; Yang, Xixiang1; Zhan, Desong1
Corresponding AuthorZhan, Desong(zhandesong@126.com)
2020-01-08
Source PublicationMATERIALS TECHNOLOGY
ISSN1066-7857
Volume35Issue:8Pages:8
AbstractObjective: Three differently designed multilayer ?lms of TiCu/TiCuN multilayer (M1, M2, and M3) were deposited on 316L stainless steel surface using the axial magnetic ?eld-enhanced arc ion plating (AMFE-ARP) method. The aim of this study was to investigate both cytocompatibility and antibacterial activity of the multilayer ?lms. Methods: The antibacterial rate, attached bacteria and developed biofilms were studied from quantitative antibacterial test and bacterial morphological examination. The in vitro biocompatibilities of the films were systematically investigated by means of methods of CCK8 cell proliferation assay, phalloidin cytoskeleton staining and Annexin-V/PI flow cytometry. Results: The multilayer ?lm of M2 revealed a better cytocompatibility and antibacterial activity than the others. The M2 ?lm is suggested to be much application potential as antibacterial ?lms on the biomedical implants.
KeywordDental implants peri-implantitis TiCu TiCuN multilayer coating arc ion plating anti-bacterial
DOI10.1080/10667857.2019.1699269
Indexed BySCI
Language英语
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, Multidisciplinary
WOS IDWOS:000505661600001
PublisherTAYLOR & FRANCIS LTD
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/136305
Collection中国科学院金属研究所
Corresponding AuthorZhan, Desong
Affiliation1.China Med Univ, Sch Stomatol, Dept Dent Mat, Shenyang, Peoples R China
2.Luohe Cent Hosp, Affiliated Hosp 1, Luohe Med Coll, Dept Stomatol, Luohe, Peoples R China
3.Chinese Acad Sci, Inst Met Res, Shenyang, Peoples R China
Recommended Citation
GB/T 7714
Wang, Jingren,Zhao, Bing,Li, Gaiming,et al. Study of TiCu/TiCuN multilayer films with antibacterial activity[J]. MATERIALS TECHNOLOGY,2020,35(8):8.
APA Wang, Jingren.,Zhao, Bing.,Li, Gaiming.,Yang, Ke.,Yu, Jiaying.,...&Zhan, Desong.(2020).Study of TiCu/TiCuN multilayer films with antibacterial activity.MATERIALS TECHNOLOGY,35(8),8.
MLA Wang, Jingren,et al."Study of TiCu/TiCuN multilayer films with antibacterial activity".MATERIALS TECHNOLOGY 35.8(2020):8.
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