Synergistic effects of Mg-substitution and particle size of chicken eggshells on hydrothermal synthesis of biphasic calcium phosphate nanocrystals

doi:10.1016/j.jmst.2019.04.038

IMR OpenIR

	Synergistic effects of Mg-substitution and particle size of chicken eggshells on hydrothermal synthesis of biphasic calcium phosphate nanocrystals
	Cui, Wei 1,2; Song, Qibin 3; Su, Huhu 1,2; Yang, Zhiqing 1,2; Yang, Rui 1,2; Li, Na 1; Zhang, Xing 1,2
通讯作者	Li, Na(lina@imr.ac.cn) ; Zhang, Xing(xingzhang@imr.ac.cn)
	2020
发表期刊	JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN	1005-0302
卷号	36 页码:27-36
摘要	Magnesium (Mg2+) ion plays important roles in biomineralization of bone, teeth and calcium carbonate skeletons. Herein, chicken eggshells mainly comprising of Mg-calcite nanocrystals (Mg/(Mg + Ca) (similar to)2.0 mol.%) were used to fabricate biphasic calcium phosphate (BCP), a mixture of hydroxyapatite (HA) and beta-tricalcium phosphate (beta-TCP) nanocrystals, through hydrothermal reactions at 200 degrees C for 24 h. Our results indicated that beta-TCP nanocrystals formed through the ion-exchange reactions of Mg-calcite, while HA nanocrystals were mainly produced by dissolution-reprecipitation reactions on the surfaces of eggshell samples in the hydrothermal system. Mg substitution in calcite resulted in formation of beta-TCP nanocrystals instead of HA crystals through ion-exchange reactions. BCP samples with different compositions ((similar to)28.6-77.8 wt.% beta-TCP) were produced by controlling particle sizes of eggshells for hydrothermal reactions. The larger particles lead to the larger proportion of beta-TCP in the BCP composition. Therefore, Mg substitution and particle size had synergetic effects on the hydrothermal synthesis of BCP using chicken eggshells through balance of ion-exchange and dissolution-reprecipitation reactions. Cell culture results showed that the BCP products were non-cytotoxic to MC3T3-E1 cells, which may be used for bone substitute materials in future. (C) 2019 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
关键词	Hydrothermal reactions Ion-exchange Dissolution-reprecipitation Nanocrystals Biphasic calcium phosphate Bone substitute materials
资助者	National Key Research and Development Program of China from Ministry of Science andTechnology ; Key Research Program of Frontier Sciences from Chinese Academy of Sciences (CAS) ; Key Research and Development Program of Liaoning Province ; Shenyang Key R&D and Technology Transfer Program
DOI	10.1016/j.jmst.2019.04.038
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China from Ministry of Science andTechnology[2016YFC1100502] ; Key Research Program of Frontier Sciences from Chinese Academy of Sciences (CAS)[QYZDJ-SSW-JSC031] ; Key Research and Development Program of Liaoning Province[2017105005] ; Shenyang Key R&D and Technology Transfer Program[Z17-7-023]
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
WOS类目	Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS记录号	WOS:000503162000004
出版者	JOURNAL MATER SCI TECHNOL
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/136463
专题	中国科学院金属研究所
通讯作者	Li, Na; Zhang, Xing
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 230026, Anhui, Peoples R China 3.China Med Univ, Dept Plast Surg, Shengjing Hosp, Shenyang 110004, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Cui, Wei,Song, Qibin,Su, Huhu,et al. Synergistic effects of Mg-substitution and particle size of chicken eggshells on hydrothermal synthesis of biphasic calcium phosphate nanocrystals[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2020,36:27-36.
APA	Cui, Wei.,Song, Qibin.,Su, Huhu.,Yang, Zhiqing.,Yang, Rui.,...&Zhang, Xing.(2020).Synergistic effects of Mg-substitution and particle size of chicken eggshells on hydrothermal synthesis of biphasic calcium phosphate nanocrystals.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,36,27-36.
MLA	Cui, Wei,et al."Synergistic effects of Mg-substitution and particle size of chicken eggshells on hydrothermal synthesis of biphasic calcium phosphate nanocrystals".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 36(2020):27-36.