IMR OpenIR
Materials evolution of bone plates for internal fixation of bone fractures: A review
Li, Junlei1; Qin, Ling2,3; Yang, Ke4; Ma, Zhijie1; Wang, Yongxuan1; Cheng, Liangliang1; Zhao, Dewei1
Corresponding AuthorZhao, Dewei(zhaodewei2016@163.com)
2020
Source PublicationJOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN1005-0302
Volume36Pages:190-208
AbstractBone plates play a vital role in bone fracture healing by providing the necessary mechanical fixation for fracture fragments through modulating biomechanical microenvironment adjacent to the fracture site. Good treatment effect has been achieved for fixation of bone fracture with conventional bone plates, which are made of stainless steel or titanium alloy. However, several limitations still exist with traditional bone plates including loosening and stress shielding due to significant difference in modulus between metal material and bone tissue that impairs optimal fracture healing. Additionally, due to demographic changes and non-physiological loading, the population suffering from refractory fractures, such as osteoporosis fractures and comminuted fractures, is increasing, which imposes a big challenge to traditional bone plates developed for normal bone fracture repair. Therefore, optimal fracture treatment with adequate fixation implants in terms of materials and design relevant to special conditions is desirable. In this review, the complex physiological process of bone healing is introduced, followed by reviewing the development of implant design and biomaterials for bone plates. Finally, we discuss recent development of hybrid bone plates that contains bioactive elements or factors for fracture healing enhancement as a promising direction. This includes biodegradable Mg-based alloy used for designing bone screw-plates that has been proven to be beneficial for fracture healing, an innovative development that attracts more and more attention. This paper also indicates that the tantalum bone plates with porous structure are also emerging as a new fracture internal fixation implants. The reduction of the stress shielding is verified to be useful to accelerate bone fracture healing. Potential application of biodegradable metals may also avoid a second operation for implant removal. Further developments in biometals and their design for orthopedic bone plates are expected to improve the treatment of bone fracture, especially the refractory fractures. (C) 2019 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
KeywordBone plate Biomaterials Biodegradable materials Titanium Magnesium Porous tantalum
Funding OrganizationNational Key R&D Programof China ; National Natural Science Foundation of China ; China Postdoctoral Science Foundation ; Doctor Initial Foundation of Liaoning Province ; Affiliated Zhongshan Hospital of Dalian University ; Research Grants Council of the Hong Kong Special Administrative Region, China
DOI10.1016/j.jmst.2019.07.024
Indexed BySCI
Language英语
Funding ProjectNational Key R&D Programof China[2016YFC1102000] ; National Natural Science Foundation of China[81672139] ; National Natural Science Foundation of China[81702129] ; China Postdoctoral Science Foundation[171479] ; Doctor Initial Foundation of Liaoning Province[20170520017] ; Affiliated Zhongshan Hospital of Dalian University[DLDXZSYYDK201701] ; Research Grants Council of the Hong Kong Special Administrative Region, China[T13-402/17-N]
WOS Research AreaMaterials Science ; Metallurgy & Metallurgical Engineering
WOS SubjectMaterials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS IDWOS:000503162000024
PublisherJOURNAL MATER SCI TECHNOL
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/136503
Collection中国科学院金属研究所
Corresponding AuthorZhao, Dewei
Affiliation1.Dalian Univ, Dept Orthopaed, Affiliated Zhongshan Hosp, Dalian 116001, Peoples R China
2.Chinese Univ Hong Kong, Musculoskeletal Res Lab, Dept Orthopaed & Traumatol, Hong Kong, Peoples R China
3.Chinese Acad Sci, Ctr Translat Med Res & Dev, Inst Biomed Engn, Shenzhen 518055, Guangdong, Peoples R China
4.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China
Recommended Citation
GB/T 7714
Li, Junlei,Qin, Ling,Yang, Ke,et al. Materials evolution of bone plates for internal fixation of bone fractures: A review[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2020,36:190-208.
APA Li, Junlei.,Qin, Ling.,Yang, Ke.,Ma, Zhijie.,Wang, Yongxuan.,...&Zhao, Dewei.(2020).Materials evolution of bone plates for internal fixation of bone fractures: A review.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,36,190-208.
MLA Li, Junlei,et al."Materials evolution of bone plates for internal fixation of bone fractures: A review".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 36(2020):190-208.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Li, Junlei]'s Articles
[Qin, Ling]'s Articles
[Yang, Ke]'s Articles
Baidu academic
Similar articles in Baidu academic
[Li, Junlei]'s Articles
[Qin, Ling]'s Articles
[Yang, Ke]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Li, Junlei]'s Articles
[Qin, Ling]'s Articles
[Yang, Ke]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.