Assessment of structure integrity, corrosion behavior and microstructure change of AZ31B stent in porcine coronary arteries

doi:10.1016/j.jmst.2018.12.017

IMR OpenIR

	Assessment of structure integrity, corrosion behavior and microstructure change of AZ31B stent in porcine coronary arteries
	Chen, Shanshan 1; Zhang, Bin 2; Zhang, Bingchun 1; Lin, Hao 1; Yang, Hui 1; Zheng, Feng 1; Chen, Ming 2; Yang, Ke 1
通讯作者	Chen, Ming(cm6141@sina.com) ; Yang, Ke(keyang@imr.ac.cn)
	2020-02-15
发表期刊	JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN	1005-0302
卷号	39 页码:39-47
摘要	Magnesium alloy coronary stent becomes a hot research topic due to its biodegradable character for avoiding late thrombosis and late restenosis. However, fracture of Mg alloy stent was a common issue after implantation. In this study, 18 drug-eluting biodegradable AZ31B stents were implanted into porcine coronary arteries to assess its structural integrity, corrosion behavior and microstructure change in vivo. The coronary artery tissue responses to AZ31B stent implantation were detected by quantitative coronary angiography and optical coherence tomography at the set time periods. In addition, further analyses were focused on the stent structure integrity, corrosion behaviors and the microstructure change of Mg alloy stents after implantation. A large number of fractures on stent struts were observed by high-resolution transmission X-ray tomography clearly. Moreover, degradation products, twins and grain refinement that appeared in Mg alloy stent matrix after implantation were also observed during the study. Inferred from this study, it is shown that the loss of AZ31B stent structural integrity may be the result of stress concentration, degradation and microstructure change. (C) 2019 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
关键词	AZ31B Coronary stent Structural integrity Degradation Microstructure
资助者	National Key Research and Development Program of China
DOI	10.1016/j.jmst.2018.12.017
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China[2016YFC1102404]
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
WOS类目	Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS记录号	WOS:000510492000006
出版者	JOURNAL MATER SCI TECHNOL
引用统计	被引频次：14[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/137149
专题	中国科学院金属研究所
通讯作者	Chen, Ming; Yang, Ke
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Peking Univ, Hosp 1, Dept Cardiol, Beijing 100034, Peoples R China
推荐引用方式 GB/T 7714	Chen, Shanshan,Zhang, Bin,Zhang, Bingchun,et al. Assessment of structure integrity, corrosion behavior and microstructure change of AZ31B stent in porcine coronary arteries[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2020,39:39-47.
APA	Chen, Shanshan.,Zhang, Bin.,Zhang, Bingchun.,Lin, Hao.,Yang, Hui.,...&Yang, Ke.(2020).Assessment of structure integrity, corrosion behavior and microstructure change of AZ31B stent in porcine coronary arteries.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,39,39-47.
MLA	Chen, Shanshan,et al."Assessment of structure integrity, corrosion behavior and microstructure change of AZ31B stent in porcine coronary arteries".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 39(2020):39-47.