IMR OpenIR
Effect of copper-doped titanium nitride coating on angiogenesis
Liu, Hui1,2; Zhang, Xiyue1,2; Jin, Shujing3; Zhao, Yanhui1; Ren, Ling1; Yang, Ke1
Corresponding AuthorZhao, Yanhui(yhzhao@imr.ac.cn) ; Ren, Ling(lren@imr.ac.cn)
2020-06-15
Source PublicationMATERIALS LETTERS
ISSN0167-577X
Volume269Pages:4
AbstractThis work studied the in vitro angiogenic response of human umbilical vein endothelial cells on the copper-doped titanium nitride (TiCuN) coating, which has been proved to own good antibacterial ability and excellent corrosion resistance as well as wear resistance. It was found that TiCuN coating had no cytotoxic effect and promoted the early cell proliferation, furthermore it significantly promoted the mRNA expressions of eNOS and VEGF, also obviously enhanced the cell migration and tube formation compared with TiN coating, which indicated that TiCuN coating can improve the angiogenesis ability of biomaterials and would gain new opportunities for the applications in orthopedic and cardiovascular fields. (C) 2020 Elsevier B.V. All rights reserved.
KeywordBiomaterials Coating Angiogenesis Human umbilical vein endothelial cells
Funding OrganizationNational Key Research and Development Program of China ; LiaoNing Revitalization Talents Program ; National Natural Science Foundation ; Key Projects for Foreign Cooperation of Bureau of International Cooperation Chinese Academy of Sciences
DOI10.1016/j.matlet.2020.127634
Indexed BySCI
Language英语
Funding ProjectNational Key Research and Development Program of China[2018YFC1106601] ; National Key Research and Development Program of China[2016YFC1100601] ; LiaoNing Revitalization Talents Program[XLYC1807069] ; National Natural Science Foundation[51631009] ; National Natural Science Foundation[31870954] ; Key Projects for Foreign Cooperation of Bureau of International Cooperation Chinese Academy of Sciences[174321KYSB2018000]
WOS Research AreaMaterials Science ; Physics
WOS SubjectMaterials Science, Multidisciplinary ; Physics, Applied
WOS IDWOS:000523600100014
PublisherELSEVIER
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/138039
Collection中国科学院金属研究所
Corresponding AuthorZhao, Yanhui; Ren, Ling
Affiliation1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
2.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 230026, Peoples R China
3.Nanjing Iron & Steel Co, Res Inst, Nanjing 210035, Peoples R China
Recommended Citation
GB/T 7714
Liu, Hui,Zhang, Xiyue,Jin, Shujing,et al. Effect of copper-doped titanium nitride coating on angiogenesis[J]. MATERIALS LETTERS,2020,269:4.
APA Liu, Hui,Zhang, Xiyue,Jin, Shujing,Zhao, Yanhui,Ren, Ling,&Yang, Ke.(2020).Effect of copper-doped titanium nitride coating on angiogenesis.MATERIALS LETTERS,269,4.
MLA Liu, Hui,et al."Effect of copper-doped titanium nitride coating on angiogenesis".MATERIALS LETTERS 269(2020):4.
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