A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg

doi:10.1016/j.colsurfb.2020.110911

IMR OpenIR

	A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg
	Li, Junlei 1; Xu, Wenwu 1; Lin, Xiao 2; Cao, Fang 1; Yang, Jiahui 1; Li, Lu 1; Wei, Xiaowei 1; Zhang, Xiuzhi 1; Zhao, Dewei 1; Yang, Ke 3
通讯作者	Zhao, Dewei(zhaodewei2016@163.com)
	2020-06-01
发表期刊	COLLOIDS AND SURFACES B-BIOINTERFACES
ISSN	0927-7765
卷号	190 页码:10
摘要	Enhanced corrosion resistance and accelerated new bone formation are desired to make Mg and its alloys to be ideal candidate for bone biomaterial. For this purpose, a CDHA/MgF2 bi-layer coating was prepared on high purity Mg by a combination of fluoride treatment and hydrothermal treatment. The coating exhibited a nanoscale surface topography. Enhanced adhesion strength and corrosion resistance was obtained for the CDHA/MgF2 bi-layer coating. In vitro cell experiment showed that the adhesion, proliferation and differentiation of MG63 cells were significantly improved on Mg with CDHA/MgF2 coating compared to that on Mg with HA coating and MgF2 coating. In conclusion, this study provides a promising surface modification method for Mg metal with enhanced corrosion resistance and superior osteogenic bioactivity.
关键词	Biodegradable Mg CDHA/MgF(2)bi-layer coating Nanorod-like morphology Corrosion resistance Osteogenic capability
资助者	National Key R&D Program of China ; National Natural Science Foundation of China ; Doctor Initial Foundation of Liaoning Province ; Affiliated Zhongshan Hospital of Dalian University
DOI	10.1016/j.colsurfb.2020.110911
收录类别	SCI
语种	英语
资助项目	National Key R&D Program of China[2016YFC1102000] ; National Natural Science Foundation of China[81672139] ; National Natural Science Foundation of China[81702129] ; Doctor Initial Foundation of Liaoning Province[20170520017] ; Affiliated Zhongshan Hospital of Dalian University[DLDXZSYYDK201701]
WOS研究方向	Biophysics ; Chemistry ; Materials Science
WOS类目	Biophysics ; Chemistry, Physical ; Materials Science, Biomaterials
WOS记录号	WOS:000530677200027
出版者	ELSEVIER
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/138735
专题	中国科学院金属研究所
通讯作者	Zhao, Dewei
作者单位	1.Dalian Univ, Dept Orthopaed, Affiliated Zhongshan Hosp, Dalian 116001, Peoples R China 2.Soochow Univ, Med Coll, Orthopaed Inst, Suzhou 215006, Jiangsu, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Li, Junlei,Xu, Wenwu,Lin, Xiao,et al. A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2020,190:10.
APA	Li, Junlei.,Xu, Wenwu.,Lin, Xiao.,Cao, Fang.,Yang, Jiahui.,...&Yang, Ke.(2020).A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg.COLLOIDS AND SURFACES B-BIOINTERFACES,190,10.
MLA	Li, Junlei,et al."A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg".COLLOIDS AND SURFACES B-BIOINTERFACES 190(2020):10.