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A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg
Li, Junlei1; Xu, Wenwu1; Lin, Xiao2; Cao, Fang1; Yang, Jiahui1; Li, Lu1; Wei, Xiaowei1; Zhang, Xiuzhi1; Zhao, Dewei1; Yang, Ke3
Corresponding AuthorZhao, Dewei(zhaodewei2016@163.com)
2020-06-01
Source PublicationCOLLOIDS AND SURFACES B-BIOINTERFACES
ISSN0927-7765
Volume190Pages:10
AbstractEnhanced corrosion resistance and accelerated new bone formation are desired to make Mg and its alloys to be ideal candidate for bone biomaterial. For this purpose, a CDHA/MgF2 bi-layer coating was prepared on high purity Mg by a combination of fluoride treatment and hydrothermal treatment. The coating exhibited a nanoscale surface topography. Enhanced adhesion strength and corrosion resistance was obtained for the CDHA/MgF2 bi-layer coating. In vitro cell experiment showed that the adhesion, proliferation and differentiation of MG63 cells were significantly improved on Mg with CDHA/MgF2 coating compared to that on Mg with HA coating and MgF2 coating. In conclusion, this study provides a promising surface modification method for Mg metal with enhanced corrosion resistance and superior osteogenic bioactivity.
KeywordBiodegradable Mg CDHA/MgF(2)bi-layer coating Nanorod-like morphology Corrosion resistance Osteogenic capability
Funding OrganizationNational Key R&D Program of China ; National Natural Science Foundation of China ; Doctor Initial Foundation of Liaoning Province ; Affiliated Zhongshan Hospital of Dalian University
DOI10.1016/j.colsurfb.2020.110911
Indexed BySCI
Language英语
Funding ProjectNational Key R&D Program of China[2016YFC1102000] ; National Natural Science Foundation of China[81672139] ; National Natural Science Foundation of China[81702129] ; Doctor Initial Foundation of Liaoning Province[20170520017] ; Affiliated Zhongshan Hospital of Dalian University[DLDXZSYYDK201701]
WOS Research AreaBiophysics ; Chemistry ; Materials Science
WOS SubjectBiophysics ; Chemistry, Physical ; Materials Science, Biomaterials
WOS IDWOS:000530677200027
PublisherELSEVIER
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/138735
Collection中国科学院金属研究所
Corresponding AuthorZhao, Dewei
Affiliation1.Dalian Univ, Dept Orthopaed, Affiliated Zhongshan Hosp, Dalian 116001, Peoples R China
2.Soochow Univ, Med Coll, Orthopaed Inst, Suzhou 215006, Jiangsu, Peoples R China
3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
Recommended Citation
GB/T 7714
Li, Junlei,Xu, Wenwu,Lin, Xiao,et al. A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2020,190:10.
APA Li, Junlei.,Xu, Wenwu.,Lin, Xiao.,Cao, Fang.,Yang, Jiahui.,...&Yang, Ke.(2020).A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg.COLLOIDS AND SURFACES B-BIOINTERFACES,190,10.
MLA Li, Junlei,et al."A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg".COLLOIDS AND SURFACES B-BIOINTERFACES 190(2020):10.
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