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Decellularized Extracellular Matrices for Tissue Engineering and Regeneration
Ge, Fang1,2; Lu, Yuhe1,3; Li, Qian1,2; Zhang, Xing1,4
Corresponding AuthorZhang, Xing(xingzhang@imr.ac.cn)
2020
Source PublicationBIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE
ISSN0065-2598
Volume1250Pages:15-31
AbstractDecellularized extracellular matrices (dECMs) from mammalian tissues and organs are particularly interesting as scaffolds for tissue engineering and regeneration when considering their ability to retain chemical compositions and three-dimensional (3D) microstructures that are similar to native ECMs. This review discusses the advantages and disadvantages of different decellularization methods that use various agents, such as ionic and nonionic detergents and biological enzymes. The applications of dECMs as scaffolds or hydrogels for tissue engineering of specific tissues including heart valves, blood vessels, and skin, as well as their performance in vitro and in vivo, are also discussed. In addition, whole organ regeneration (i.e., the heart, kidney, liver) using dECM scaffolds has been explored, which are able to recapitulate partial functions of native organs.
KeywordDecellularization Recellularization Extracellular matrices Microstructure Tissue engineering Organ regeneration
DOI10.1007/978-981-15-3262-7_2
Indexed BySCI
Language英语
WOS Research AreaCell Biology ; Materials Science
WOS SubjectCell & Tissue Engineering ; Materials Science, Biomaterials
WOS IDWOS:000556133600003
PublisherSPRINGER-VERLAG SINGAPORE PTE LTD
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/140141
Collection中国科学院金属研究所
Corresponding AuthorZhang, Xing
Affiliation1.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China
2.Northeastern Univ, Dept Chem, Shenyang, Liaoning, Peoples R China
3.Northeastern Univ, Sch Mat Sci & Engn, Shenyang, Liaoning, Peoples R China
4.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei, Anhui, Peoples R China
Recommended Citation
GB/T 7714
Ge, Fang,Lu, Yuhe,Li, Qian,et al. Decellularized Extracellular Matrices for Tissue Engineering and Regeneration[J]. BIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE,2020,1250:15-31.
APA Ge, Fang,Lu, Yuhe,Li, Qian,&Zhang, Xing.(2020).Decellularized Extracellular Matrices for Tissue Engineering and Regeneration.BIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE,1250,15-31.
MLA Ge, Fang,et al."Decellularized Extracellular Matrices for Tissue Engineering and Regeneration".BIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE 1250(2020):15-31.
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