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PREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO2 HYBRID COATING
Alternative TitlePREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO_2 HYBRID COATING
Zhang Jingying1; Qi Min3; Yang Dayi3; Ai Hongjun1
2011
Source PublicationACTA METALLURGICA SINICA
ISSN0412-1961
Volume47Issue:4Pages:429-434
AbstractTo improve the binding and osteogenic properties for the hydroxyapatite (HA) coating on Ti substrate, a ZnHA biological coating was prepared on commercially pure Ti by sol gel method after a treatment by micro-arc oxidation (MAO) to produce an porous titania (TiO2) coating on Ti. The morphologies and phases components of the coating were characterized by SEM and XRD. The release concentration of Zn2+ was measured by flame atomic absorption spectrometry. In vitro co-culture assays were performed to evaluate the cell proliferation and adhesion of MG-63 cells to the coated Ti. The proliferation rates of the cells were found to be significantly higher on the ZnHA/TiO2-2 and ZnHA/TiO2-3 coatings than that of the control group (HA) by MTT. It was confirmed by the fluorescence microscopy observations that the osteoblast like cells on the hybrid coating were favorably adhered and spread. The results suggest that the ZnHA/TiO2 hybrid coatings on Ti implants should possess better binding property and biocompatibility.
KeywordSTRUCTURAL-CHARACTERIZATION ZINC TITANIUM IMPLANTS OXIDATION SURFACES CELLS Zn Ti TiO2 hydroxyapatite osteoblast biocompatibility
Indexed ByCSCD
Language英语
CSCD IDCSCD:4181880
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/141689
Collection中国科学院金属研究所
Affiliation1.中国科学院金属研究所
2.大连大学
3.大连理工大学
Recommended Citation
GB/T 7714
Zhang Jingying,Qi Min,Yang Dayi,et al. PREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO2 HYBRID COATING[J]. ACTA METALLURGICA SINICA,2011,47(4):429-434.
APA Zhang Jingying,Qi Min,Yang Dayi,&Ai Hongjun.(2011).PREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO2 HYBRID COATING.ACTA METALLURGICA SINICA,47(4),429-434.
MLA Zhang Jingying,et al."PREPARATION AND BIOCOMPATIBILITY OF ZnHA/TiO2 HYBRID COATING".ACTA METALLURGICA SINICA 47.4(2011):429-434.
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