Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors

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	Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors
其他题名	Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors
	Liu Yan 1; Zhong Wu 1; Li Song 1
	2012
发表期刊	CHINESE CHEMICAL LETTERS
ISSN	1001-8417
卷号	23 期号:2 页码:133-136
摘要	A short and efficient synthesis of (Z)-2-substituted-5-(4-((2-substitued-5-oxoimidazolidin-4-ylidene)methyl)benzamido)benzoic acid derivatives (8a-g) as potential type of FabH inhibitors is described. Their structures were confirmed by MS, NOE and H-1 NMR. (C) 2011 Wu Zhong. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
其他摘要	A short and efficient synthesis of(Z)-2-substituted-5-(4-((2-substitued-5-oxoimidazolidin-4-ylidene)methyl)benzamido)ben-zoic acid derivatives(8a-g) as potential type of FabH inhibitors is described.Their structures were confirmed by MS,NOE and ~1H NMR.
关键词	FATTY-ACID SYNTHASE TUBERCULOSIS CLONING Tuberculosis Mycobacterium tuberculosis FabH Enzyme inhibitor Synthesis NOE
收录类别	CSCD
语种	英语
资助项目	[National High Technology Research and Development Program of China]
CSCD记录号	CSCD:4448329
引用统计	被引频次：1[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/142379
专题	中国科学院金属研究所
作者单位	1.Beijing Institute Pharmacol & Toxicol, Lab Comp Aided Drug Design & Discovery, Beijing 100850, Peoples R China 2.中国科学院金属研究所
推荐引用方式 GB/T 7714	Liu Yan,Zhong Wu,Li Song. Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors[J]. CHINESE CHEMICAL LETTERS,2012,23(2):133-136.
APA	Liu Yan,Zhong Wu,&Li Song.(2012).Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors.CHINESE CHEMICAL LETTERS,23(2),133-136.
MLA	Liu Yan,et al."Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors".CHINESE CHEMICAL LETTERS 23.2(2012):133-136.