Duration of hypertension is associated with cognitive function: a cross-sectional study in Chinese adults

IMR OpenIR

	Duration of hypertension is associated with cognitive function: a cross-sectional study in Chinese adults
其他题名	Duration of hypertension is associated with cognitive function: a crosssectional study in Chinese adults
	Li Tuo 1; Bai Yu 2; Xiang Junwu 3; Wang Rui 4; Bai Jie 5; Tuo Xiping 5; Zhao Zhongxin 1
	2014
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
卷号	127 期号:11 页码:2105-2110
摘要	Background Hypertension (HTN) is a very prevalent public health problem and as the population ages, cognitive impairment (Cl) is also going to be a public health burden. However, the relationship between hypertension duration and cognitive function declination worldwide is still unknown. The aim of the study was to investigate the effects of HTN duration on CI in Chinese population.
其他摘要	Background Hypertension (HTN) is a very prevalent public health problem and as the population ages, cognitive impairment (CI) is also going to be a public health burden. However, the relationship between hypertension duration and cognitive function declination worldwide is still unknown. The aim of the study was to investigate the effects of HTN duration on CI in Chinese population. Methods At baseline, 1 386 HTN patients and 293 normotensive (NT) people were enrolled. The HTN patients were further divided into four subgroups (duration of HTN 20 years) according to the HTN duration and were screened for cognitive function with neuropsychological tests including mini-mental-stateexamination (MMSE) and clock-drawing-test (CDT) in comparison with the NT group. Results More HTN patients had CI (45.3%) than NT subjects (30.4%), and increased with HTN duration (P <0.000 1). Compared with the scores of MMSE and CDT in the NT group, the declines were higher in the HTN patients (P <0.000 1), and in the four HTN subgroups, both MMSE and CDT scores fall when the HTN duration increased (P <0.05). Furthermore, in the HTN population without CI, the trend in alteration of CI was relatively mild but still existed (P <0.05). Conclusion People with HTN are more likely to have CI and the possibility and aggravation increases the prolongation of HTN duration, both in amnesic and nonamnesic function.
关键词	BLOOD-PRESSURE RISK-FACTORS IMPAIRMENT DEMENTIA METAANALYSIS ENTITY cognition impairment hypertension duration mini-mental-state-examination clock-drawing-test epidemiology
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:5154423
引用统计	被引频次：2[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/143324
专题	中国科学院金属研究所
作者单位	1.上海长征医院 2.Changhai Hosp, Department Gastroenterol, Shanghai 200433, Peoples R China 3.中国科学院金属研究所 4.Second Mil Med University, Dept Hlth Stat, Shanhgai 200433, Peoples R China 5.Changhai Hosp, Department Geriatr, Shanghai 200433, Peoples R China
推荐引用方式 GB/T 7714	Li Tuo,Bai Yu,Xiang Junwu,et al. Duration of hypertension is associated with cognitive function: a cross-sectional study in Chinese adults[J]. CHINESE MEDICAL JOURNAL,2014,127(11):2105-2110.
APA	Li Tuo.,Bai Yu.,Xiang Junwu.,Wang Rui.,Bai Jie.,...&Zhao Zhongxin.(2014).Duration of hypertension is associated with cognitive function: a cross-sectional study in Chinese adults.CHINESE MEDICAL JOURNAL,127(11),2105-2110.
MLA	Li Tuo,et al."Duration of hypertension is associated with cognitive function: a cross-sectional study in Chinese adults".CHINESE MEDICAL JOURNAL 127.11(2014):2105-2110.