| Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA | |
| Alternative Title | Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA |
| Pan LeiTing1; Sun WenWu2; Qi JiWei1; Wu Xian1; Song Kun1; Hu Fen1; Zhang XinZheng1; Xu JingJun1 | |
| 2009 | |
| Source Publication | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
 |
| ISSN | 1000-3282 |
| Volume | 36Issue:1Pages:83-87 |
| Abstract | Rat synoviocytes were cultured in vitro and the changing of cellular cytoskeleton induced by PMA was investigated with atomic force microscopy. PMA is usually used to stimulate PKC signal transduction pathway in synoviocytes and to simulate process of inflammation. The results presented here show that synoviocyte cytoskeleton has changed significantly after PKC activation by using the imaging of atomic force microscopy. The results also indicate that the activation of PKC might play crucial role in cytoskeleton changing of synoviocytes, which, to some extent, provides some experiments and ideas on understanding the mechanism underlying rheumatoid arthritis (RA). |
| Keyword | ATOMIC-FORCE MICROSCOPY PROTEIN-KINASE-C RHEUMATOID-ARTHRITIS CORTICAL CYTOSKELETON SYNOVIAL FIBROBLASTS ACTIN CYTOSKELETON CELLS ACTIVATION synoviocytes cytoskeleton PMA PKC atomic force microscopy |
| Indexed By | CSCD |
| Language | 英语 |
| Funding Project | [National Basic Research Program of China] ; [Key International S&T Cooperation Project of China] ; [Programme of Introducing Talents of Displine to Universities] |
| CSCD ID | CSCD:3487928 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/144178 |
| Collection | 中国科学院金属研究所 |
| Affiliation | 1.南开大学 2.中国科学院金属研究所 |
| Recommended Citation GB/T 7714 | Pan LeiTing,Sun WenWu,Qi JiWei,et al. Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2009,36(1):83-87. |
| APA | Pan LeiTing.,Sun WenWu.,Qi JiWei.,Wu Xian.,Song Kun.,...&Xu JingJun.(2009).Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,36(1),83-87. |
| MLA | Pan LeiTing,et al."Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 36.1(2009):83-87. |
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