Antifouling coating with low surface energy is an important branch of marine coatings. In the present work, an organosilicone modified acrylic resin was used as coating matrix and nano SiO2 was used as filler to prepare an antifouling coating with low surface energy. The effect of silicone monomer content on the properties of the modified acrylic resin was investigated. It was found that with the increase of silicone monomer content, the viscosity of the modified acrylic resin de- creases, while the water contact angle of the modified acrylic resin increases. The effect of nano SiO2 content on the coat- ing morphology and water contact angle was studied. The results show that the addition of small amount of nano SiO2 （ 1% and 3 % ） that was treated by fluorosilane can significantly increase water contact angle and improve the anti-fouling proper- ty of the coatings. The water contact angle of polyurethane coating with addition of nano SiO2 paste is higher than that of polyurethane coating with addition of fluorosilane modified SiO2 , while the later is higher than that of polyurethane coating with addition of unmodified SiO2. When the contents of nano SiO2 are 1% and 3% , the water contact angles of the coat- ings reach 101.8°and 103° , respectively. The dispersed nano SiO2 in concentrated paste contributes to the micro-nano structure of coating surface, which benefits the anti-fouling property.