Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway | |
Alternative Title | Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway |
Li Zhao; Zhu Xiaoying; Li Meng; Bai Yinglong; Hu Jian | |
2008 | |
Source Publication | CHINESE MEDICAL JOURNAL
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ISSN | 0366-6999 |
Volume | 121Issue:22Pages:2299-2304 |
Abstract | Background Studies suggested that exogenous ghrelin administration could prevent early left ventricular remodeling in rats with myocardial infarction. We investigated herein whether ghrelin attenuated left ventricular remodeling induced by hypertension and whether ghrelin's effect was mediated through the peroxisome proliferator-activated receptor gamma (PPAR-gamma)-dependent pathway. |
Other Abstract | Studies suggested that exogenous ghrelin administration could prevent early left ventricular remodeling in rats with myocardial infarction. We investigated herein whether ghrelin attenuated left ventricular remodeling induced by hypertension and whether ghrelin’s effect was mediated through the peroxisome proliferator-activated receptor gamma (PPAR-γ?)-dependent pathway. |
Keyword | HEART-FAILURE MACROPHAGES DYSFUNCTION MYOCARDIUM CACHEXIA PEPTIDE ALPHA ACID ghrelin hypertension collagen peroxisome proliferator-activated receptor gamma left ventricular remodeling |
Indexed By | CSCD |
Language | 英语 |
CSCD ID | CSCD:3477112 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.imr.ac.cn/handle/321006/146080 |
Collection | 中国科学院金属研究所 |
Affiliation | 中国科学院金属研究所 |
Recommended Citation GB/T 7714 | Li Zhao,Zhu Xiaoying,Li Meng,et al. Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway[J]. CHINESE MEDICAL JOURNAL,2008,121(22):2299-2304. |
APA | Li Zhao,Zhu Xiaoying,Li Meng,Bai Yinglong,&Hu Jian.(2008).Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway.CHINESE MEDICAL JOURNAL,121(22),2299-2304. |
MLA | Li Zhao,et al."Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway".CHINESE MEDICAL JOURNAL 121.22(2008):2299-2304. |
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