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Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway
Alternative TitleProtective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway
Li Zhao; Zhu Xiaoying; Li Meng; Bai Yinglong; Hu Jian
2008
Source PublicationCHINESE MEDICAL JOURNAL
ISSN0366-6999
Volume121Issue:22Pages:2299-2304
AbstractBackground Studies suggested that exogenous ghrelin administration could prevent early left ventricular remodeling in rats with myocardial infarction. We investigated herein whether ghrelin attenuated left ventricular remodeling induced by hypertension and whether ghrelin's effect was mediated through the peroxisome proliferator-activated receptor gamma (PPAR-gamma)-dependent pathway.
Other AbstractStudies suggested that exogenous ghrelin administration could prevent early left ventricular remodeling in rats with myocardial infarction. We investigated herein whether ghrelin attenuated left ventricular remodeling induced by hypertension and whether ghrelin’s effect was mediated through the peroxisome proliferator-activated receptor gamma (PPAR-γ?)-dependent pathway.
KeywordHEART-FAILURE MACROPHAGES DYSFUNCTION MYOCARDIUM CACHEXIA PEPTIDE ALPHA ACID ghrelin hypertension collagen peroxisome proliferator-activated receptor gamma left ventricular remodeling
Indexed ByCSCD
Language英语
CSCD IDCSCD:3477112
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/146080
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Li Zhao,Zhu Xiaoying,Li Meng,et al. Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway[J]. CHINESE MEDICAL JOURNAL,2008,121(22):2299-2304.
APA Li Zhao,Zhu Xiaoying,Li Meng,Bai Yinglong,&Hu Jian.(2008).Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway.CHINESE MEDICAL JOURNAL,121(22),2299-2304.
MLA Li Zhao,et al."Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway".CHINESE MEDICAL JOURNAL 121.22(2008):2299-2304.
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