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Prospective multi-center study of female patients with ST-elevation myocardial infarction in Liaoning province, China
Alternative TitleProspective multi-center study of female patients with ST-elevation myocardial infarction in Liaoning province, China
Zhang Bo1; Jiang Daming2; Zhou Xuchen1; Liu Jun1; Zhang Wei3; Sun Yujiao4; Ren Lina4; Zhang Zhihong4; Gao Yuan4; Li Yuze4; Shi Jingpu4; Qi Guoxian4
2012
Source PublicationCHINESE MEDICAL JOURNAL
ISSN0366-6999
Volume125Issue:11Pages:1915-1919
AbstractBackground In cardiology, it is controversial whether gender influences prognosis after acute myocardial infarction (MI). We examined the 30-day and 1-year prognosis for female patients with ST-elevation myocardial infarction (STEMI) in Liaoning province, and we analyzed factors that influenced these outcomes.
Other AbstractBackground In cardiology, it is controversial whether gender influences prognosis after acute myocardial infarction (MI). We examined the 30-day and 1-year prognosis for female patients with ST-elevation myocardial infarction (STEMI) in Liaoning province, and we analyzed factors that influenced these outcomes. Methods This was a prospective, multicenter, observational study in which patient data were collected by questionnaire at the time of diagnosis and at approximately 30 days and 1 year later by telephone inquiries. Patients were diagnosed with STEMI between June 1, 2009 and June 1, 2010 at any of the 20 hospitals that gave treatment representative of current STEMI treatment in Liaoning Province. Unified follow-up questionnaire was used to visit the STEMI patients. Results We analyzed data from a total of 1429 consecutive patients with STEMI in Liaoning province. Female patients were older (70.0 vs. 60.3, P <0.001) and were less likely to receive emergency reperfusion therapy than male ones (39.2% vs. 58.0%, P <0.001). Female gender was associated with higher unadjusted 30-day mortality rates (HR=2.118, 95%CI: 1.572-2.854, P <0.001) and higher unadjusted 1-year mortality rates (HR=2.174, 95%CI: 1.659-2.848, P <0.001). Multivariate Cox regression analysis showed that female gender was not an independent predictor of 30-day mortality rates (HR=1.273, 95%CI: 0.929-1.745, P=0.133) nor of 1-year mortality rates (HR=1.112, 95%CI: 0.831-1.487, P=0.475). Conclusions Women with STEMI appear to be at increased risk of 30-day and 1-year mortality compared with male STEMI patients, but this difference may be explained by older age and less frequent receipt of reperfusion therapy among the women.
KeywordPERCUTANEOUS CORONARY INTERVENTION GENDER-BASED DIFFERENCES WOMEN ANGIOPLASTY REGISTRY DEATH myocardial infarction female reperfusion mortality
Indexed ByCSCD
Language英语
Funding Project[Science and Technology Planning Project of Liaoning Province, China]
CSCD IDCSCD:4550374
Citation statistics
Cited Times:3[CSCD]   [CSCD Record]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/146198
Collection中国科学院金属研究所
Affiliation1.Dalian Med University, Affiliated Hosp 1, Dept Cardiol, Dalian 116011, Liaoning, Peoples R China
2.Dandong Ctr Hosp, Department Cardiol, Dandong 118000, Liaoning, Peoples R China
3.Dalian Med University, Affiliated Hosp 1, Dept VIP, Dalian 116011, Liaoning, Peoples R China
4.中国科学院金属研究所
Recommended Citation
GB/T 7714
Zhang Bo,Jiang Daming,Zhou Xuchen,et al. Prospective multi-center study of female patients with ST-elevation myocardial infarction in Liaoning province, China[J]. CHINESE MEDICAL JOURNAL,2012,125(11):1915-1919.
APA Zhang Bo.,Jiang Daming.,Zhou Xuchen.,Liu Jun.,Zhang Wei.,...&Qi Guoxian.(2012).Prospective multi-center study of female patients with ST-elevation myocardial infarction in Liaoning province, China.CHINESE MEDICAL JOURNAL,125(11),1915-1919.
MLA Zhang Bo,et al."Prospective multi-center study of female patients with ST-elevation myocardial infarction in Liaoning province, China".CHINESE MEDICAL JOURNAL 125.11(2012):1915-1919.
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