Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists

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	Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists
其他题名	Design, synthesis and biological evaluation of 1,4-dihydrothieno3′,2′:5,6thiopyrano4,3- cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists
	Sun Rui 1; Song Jing 1; Liu Si Jie 1; Zhao Hui 1; Yan Chun Li 1; Zhang Ai Jun 1; Koirala Diwa 3; Li Da Wei 3; Hu Chun 1
	2011
发表期刊	CHINESE CHEMICAL LETTERS
ISSN	1001-8417
卷号	22 期号:3 页码:256-259
摘要	The estrogen receptor is a target for therapeutic agents for hormone replacement in menopausal women, osteoporosis, reproductive cancers such as breast cancer, uterine cancer and prostate cancer. 1,4-Dihydrothieno3',2':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives were designed, synthesized and biological evaluated as potential estrogen receptor antagonists. (C) 2010 Chun Hu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
其他摘要	The estrogen receptor is a target for therapeutic agents for hormone replacement in menopausal women, osteoporosis, reproductive cancers such as breast cancer, uterine cancer and prostate cancer. 1,4-Dihydrothieno3',2':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives were designed, synthesized and biological evaluated as potential estrogen receptor antagonists
关键词	BETA Estrogen receptor antagonists Synthesis Biological activity Thiophene Pyrazole Thiopyran Piperazine
收录类别	CSCD
语种	英语
资助项目	[National Natural Science Foundation of China (NSFC)]
CSCD记录号	CSCD:4149926
引用统计	被引频次：1[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/151614
专题	中国科学院金属研究所
作者单位	1.上海市地震局 2.中国科学院金属研究所 3.上海交通大学
推荐引用方式 GB/T 7714	Sun Rui,Song Jing,Liu Si Jie,et al. Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists[J]. CHINESE CHEMICAL LETTERS,2011,22(3):256-259.
APA	Sun Rui.,Song Jing.,Liu Si Jie.,Zhao Hui.,Yan Chun Li.,...&Hu Chun.(2011).Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists.CHINESE CHEMICAL LETTERS,22(3),256-259.
MLA	Sun Rui,et al."Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists".CHINESE CHEMICAL LETTERS 22.3(2011):256-259.