Diagnosis of Malignancy of Adult Mediastinal Tumors by Conventional and Transesophageal Echocardiography

IMR OpenIR

	Diagnosis of Malignancy of Adult Mediastinal Tumors by Conventional and Transesophageal Echocardiography
其他题名	Diagnosis of Malignancy of Adult Mediastinal Tumors by Conventional and Transesophageal Echocardiography
	Zhou WeiWei; Wang HongWei; Liu NanNan; Li JingJing; Yuan Wei; Zhao Rui; Xiang LiangBi; Qi Miao
	2015
发表期刊	Chinese Medical Journal
ISSN	0366-6999
卷号	128 期号:8 页码:1047-1051
摘要	Background: Transesophageal echocardiography (TEE) is a well-established method for detecting and diagnosing heart tumors. In contrast, its role in assessing the presence, growth and evidence of malignant tumors originating from mediastinal sites remains unclear. The aim of this study was to compare the diagnostic impact of TEE and transthoracic echocardiography (TTE) for determining the localization, growth and malignancy of adult mediastinal tumors (MTs). Methods: In a prospective and investigator-blinded study, we evaluated 144 consecutive patients with MT lesions to assess the diagnostic impact of TEE and TTE for detecting the presence of tumors spreading both inside and outside of the heart and for determining infiltration and invasion using pathological examination results as a reference. Results: All tumor lesions were diagnosed and carefully evaluated by biopsy. Biopsy revealed malignant tumors in 79 patients and benign tumors in 65 patients. When compared to histological findings, TEE predicted malignancy from the presence of tumors spreading both inside and outside of the heart and from infiltration and invasion in 49/79 patients (62.0%). TTE predicted malignancy in only 8/79 patients (10.1%, P 0.05); TEE detected medium MTs better than TTE (P < 0.001). Conclusions: TEE is effective and superior to TTE for predicting the localization and growth of MTs as well as for accessing evidence of tumor malignancy. TTE and TEE were able to detect anterior MTs; TEE was able to detect medium MT better than TTE.
其他摘要	Background: Transesophageal echocardiography (TEE) is a well-established method for detecting and diagnosing heart tumors. In contrast, its role in assessing the presence, growth and evidence of malignant tumors originating from mediastinal sites remains unclear. The aim of this study was to compare the diagnostic impact of TEE and transthoracic echocardiography (TTE) for determining the localization, growth and malignancy of adult mediastinal tumors (MTs). Methods: In a prospective and investigator-blinded study, we evaluated 144 consecutive patients with MT lesions to assess the diagnostic impact of TEE and TTE for detecting the presence of tumors spreading both inside and outside of the heart and for determining infiltration and invasion using pathological examination results as a reference. Results: All tumor lesions were diagnosed and carefully evaluated by biopsy. Biopsy revealed malignant tumors in 79 patients and benign tumors in 65 patients. When compared to histological findings, TEE predicted malignancy from the presence of tumors spreading both inside and outside of the heart and from infiltration and invasion in 49 P < 0.005). TEE visualized tumor lesions in 130 patients (90.3%) while the TTE visualized tumor lesions in 110 patients (76.4%) and was less effective at detecting MT lesions ( P < 0.001). TTE and TEE could detect anterior MTs and adequately verified MTs ( P > 0.05); TEE detected medium MTs better than TTE ( P < 0.001). Conclusions: TEE is effective and superior to TTE for predicting the localization and growth of MTs as well as for accessing evidence of tumor malignancy. TTE and TEE were able to detect anterior MTs; TEE was able to detect medium MT better than TTE.
关键词	Adult Medicine R Mediastinal Tumors Transesophageal Echocardiography Transthoracic Echocardiography
收录类别	CSCD
语种	英语
资助项目	[Foundation of State Key Laboratory of Robotics]
CSCD记录号	CSCD:5426185
引用统计	被引频次：1[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/152103
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Zhou WeiWei,Wang HongWei,Liu NanNan,et al. Diagnosis of Malignancy of Adult Mediastinal Tumors by Conventional and Transesophageal Echocardiography[J]. Chinese Medical Journal,2015,128(8):1047-1051.
APA	Zhou WeiWei.,Wang HongWei.,Liu NanNan.,Li JingJing.,Yuan Wei.,...&Qi Miao.(2015).Diagnosis of Malignancy of Adult Mediastinal Tumors by Conventional and Transesophageal Echocardiography.Chinese Medical Journal,128(8),1047-1051.
MLA	Zhou WeiWei,et al."Diagnosis of Malignancy of Adult Mediastinal Tumors by Conventional and Transesophageal Echocardiography".Chinese Medical Journal 128.8(2015):1047-1051.