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Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial
Liu Shiwei1; Guo Jie1; Wu Weikang2; Chen Zeliang3; Zhang Ning1
2019
Source PublicationCHINESE JOURNAL OF INTEGRATIVE MEDICINE
ISSN1672-0415
Volume25Issue:1Pages:16-22
AbstractObjectiveTo evaluate Chinese medicine (CM) formula Bazheng Powder (???) as an alternative therapeutic option for female patients with recurrent urinary tract infection (RUTI).MethodsA randomized double-blinded trial was performed. Eligible female patients with RUTI were recruited from one hospital and two community health centers. By using a blocked randomization scheme, participants were randomized to receive a CM formula (10 herbs) for 4 weeks or antibiotics for 1 week, followed by 3 weeks of placebo. Clinical cure rate and microbiological cure and recurrence after treatment were evaluated.ResultsA total 122 eligible patients were enrolled, with 61 cases in each group. The clinical cure rate by the intentto- treatment approach was 90.2% for the CM group and 82.0% for the antibiotics group (P>0.05). Bacteria were cleared from 88.5% (54/61) of patients in the CM group and 82.0% (50/61) in the antibiotics group. The recurrence rate in recovered patients at the 6-month follow-up was 9.1% (5/61) and 14.0 (7/61) in the CM and antibiotics groups, respectively (P>0.05).ConclusionCM formula Bazheng Powder is a good alternative option for RUTI treatment. (Registration No. NCT01745328)
KeywordDIAGNOSIS Chinese medicine recurrent urinary tract infection randomized control trial
Indexed ByCSCD
Language英语
Funding Project[Chinese Academy of Traditional Chinese Medicine Joint Innovation Research Project] ; [Traditional Chinese Medicine Dominant Disease Clinical Research Project] ; [Capital Featured Clinical Application and Promotion Project, China]
CSCD IDCSCD:6410946
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/153684
Collection中国科学院金属研究所
Affiliation1.Chinese Acad Chinese Med Sci, Wangjing Hosp, Department Nephrol & Endocrinol, Beijing 100102, Peoples R China Wangjing Hosp Department Nephrol & Endocrinol
2.中国科学院广州地球化学研究所
3.Acad Mil Med Sci, Institute Dis Control & Prevent, Beijing 100071, Peoples R China
4.中国科学院金属研究所
Recommended Citation
GB/T 7714
Liu Shiwei,Guo Jie,Wu Weikang,et al. Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2019,25(1):16-22.
APA Liu Shiwei,Guo Jie,Wu Weikang,Chen Zeliang,&Zhang Ning.(2019).Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial.CHINESE JOURNAL OF INTEGRATIVE MEDICINE,25(1),16-22.
MLA Liu Shiwei,et al."Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 25.1(2019):16-22.
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