Choledochoscope manometry about different drugs on the Sphincter of Oddi

IMR OpenIR

	Choledochoscope manometry about different drugs on the Sphincter of Oddi
其他题名	Choledochoscope manometry about different drugs on the Sphincter of Oddi
	Kong Jing; Wu ShuoDong; Zhang XiaoBo; Li ZhenSheng; Shi Gang; Wang Wei; Chen JunZhi
	2008
发表期刊	WORLD JOURNAL OF GASTROENTEROLOGY
ISSN	1007-9327
卷号	14 期号:38 页码:5907-5912
摘要	AIM: To assess the effects of H(2)-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents on the human Sphincter of Oddi (SO) motility by choledochoscope manometry.
其他摘要	AIM: To assess the effects of H2-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents on the human Sphincter of Oddi (SO) motility by choledochoscope manometry.METHODS: One hundred and seventy-five patients with T tube installed after cholecystectomy and choledochotomy were assessed by choledochoscope manometry. They were randomly assigned into groups of H2-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents. The Sphincter of Oddi basal pressure (SOBP), amplitude (SOCA), frequency of contractions (SOF), duodenal pressure (DP), and common bile duct pressure (CBDP) were scored and analyzed.RESULTS: SOBP and SOCA were significantly decreased after Cimetidine administration, and no statistical difference was seen in the Famotidine group. In the Gabexate mesilate group, SOBP had decreased significantly. In the Ulinastatin group, SOCA decreased when Ulinastatin was given at the rate of 2500 U/min; when Ulinastatin administration was raised to 5000 U/ min, SOBP, SOF and SOCA all experienced a fall. SOBP and SOCA for Domperidone and SOCA for Mosapride groups all decreased distinctly after administration.CONCLUSION: The regular dosage of Cimetidine showed an inhibitory effect on the motility of SO, while Pamotidine had no obvious effects otherwise. Gabnexata mesilate, Ulinastatin and gastro kinetic agents also showed inhibitory effects on the SO motility.
关键词	ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY RECEPTOR AGONIST MOTILITY PRESSURE PANCREATITIS SOMATOSTATIN HISTAMINE GABEXATE MORPHINE Sphincter of Oddi Medicamentum Choledochoscope manometry
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:3431838
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/154425
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Kong Jing,Wu ShuoDong,Zhang XiaoBo,et al. Choledochoscope manometry about different drugs on the Sphincter of Oddi[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2008,14(38):5907-5912.
APA	Kong Jing.,Wu ShuoDong.,Zhang XiaoBo.,Li ZhenSheng.,Shi Gang.,...&Chen JunZhi.(2008).Choledochoscope manometry about different drugs on the Sphincter of Oddi.WORLD JOURNAL OF GASTROENTEROLOGY,14(38),5907-5912.
MLA	Kong Jing,et al."Choledochoscope manometry about different drugs on the Sphincter of Oddi".WORLD JOURNAL OF GASTROENTEROLOGY 14.38(2008):5907-5912.