| Computer aided modeling and pore distribution of bionic porous bone structure | |
| Alternative Title | Computer aided modeling and pore distribution of bionic porous bone structure |
| Li Hu1; Yang Jianyu1; Su Pengcheng2; Wang Wanshan1 | |
| 2012 | |
| Source Publication | JOURNAL OF CENTRAL SOUTH UNIVERSITY
 |
| ISSN | 2095-2899 |
| Volume | 19Issue:12Pages:3492-3499 |
| Abstract | Artificial bone with porous structure is crucial for tissue scaffold and clinic implants. Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure. A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture, porosity and pore size. To simulate intricate bone structure, different constructive units were presented. In modeling process, bone contour was gotten from computed tomography (CT) images and was divided into two levels. Each level was represented by relatively reconstructive process. Pore size distribution was controlled by using mesh generation. The whole hexahedral mesh was reduced by unit structure, when a 3D mesh with various hexahedral elements was provided. The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way. |
| Other Abstract | Artificial bone with porous structure is crucial for tissue scaffold and clinic implants. Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure. A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture, porosity and pore size. To simulate intricate bone structure, different constructive units were presented. In modeling process, bone contour was gotten from computed tomography (CT) images and was divided into two levels. Each level was represented by relatively reconstructive process. Pore size distribution was controlled by using mesh generation. The whole hexahedral mesh was reduced by unit structure, when a 3D mesh with various hexahedral elements was provided. The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way. |
| Keyword | FINITE-ELEMENT TISSUE SCAFFOLD DESIGN CELLS tissue scaffold geometry modeling porous structure compute aided design optimal design clinic implants |
| Indexed By | CSCD |
| Language | 英语 |
| Funding Project | [State International Cooperation Program of China] ; [Basic Research Foundation of Education Ministry of China] |
| CSCD ID | CSCD:4705812 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/154920 |
| Collection | 中国科学院金属研究所 |
| Affiliation | 1.东北大学 2.中国科学院金属研究所 |
| Recommended Citation GB/T 7714 | Li Hu,Yang Jianyu,Su Pengcheng,et al. Computer aided modeling and pore distribution of bionic porous bone structure[J]. JOURNAL OF CENTRAL SOUTH UNIVERSITY,2012,19(12):3492-3499. |
| APA | Li Hu,Yang Jianyu,Su Pengcheng,&Wang Wanshan.(2012).Computer aided modeling and pore distribution of bionic porous bone structure.JOURNAL OF CENTRAL SOUTH UNIVERSITY,19(12),3492-3499. |
| MLA | Li Hu,et al."Computer aided modeling and pore distribution of bionic porous bone structure".JOURNAL OF CENTRAL SOUTH UNIVERSITY 19.12(2012):3492-3499. |
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