Synthesis of 3-benzyloxy-6-methyl-7-methoxyphenanthrene-9-carboxaldehyde with utilize intramolecular Heck reaction as the key step

IMR OpenIR

	Synthesis of 3-benzyloxy-6-methyl-7-methoxyphenanthrene-9-carboxaldehyde with utilize intramolecular Heck reaction as the key step
其他题名	Synthesis of 3-Benzyloxy-6-methyl-7-methoxyphenanthrene-9-carboxaldehyde with Utilize Intramolecular Heck Reaction as the Key Step
	Song Yanling 1; Zhai Xin 1; Sun Zhifeng 1; Kim Sanghee 2; Gong Ping 1
	2008
发表期刊	CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
ISSN	1005-9040
卷号	24 期号:4 页码:445-448
摘要	The substituted phenanthrene-9-carboxyaldehydes are very important intermediates for the syntheses of phenanthroindolizidine and phenanthroquinolizidine alkaloids. The novel title compound was prepared from the reaction of 5 steps starting from the condensation of 3-methoxyl-4-methyl-phenylacetic acid and 4-(benzyloxy)-2-iodo-benzaldehyde, followed by esterification, cyclization, reduction, and oxidation. A new method for the preparation of phenanthrene ring via palladium-catalyzed intramolecular Heck reaction was described. The title compound was characterized by IR, (1)H NMR, (13)C NMR, elemental analysis, and MS.
其他摘要	The substituted phenanthrene-9-carboxyaldehydes are very important intermediates for the syntheses of phenanthroindolizidine and phenanthroquinolizidine alkaloids. The novel title compound was prepared from the reaction of 5 steps starting from the condensation of 3-methoxyl-4-methyl-phenylacetic acid and 4-(benzyloxy)-2-iodo-benzaldehyde,followed by esterification,cyclization,reduction,and oxidation. A new method for the preparation of phenanthrene ring via palladium-catalyzed intramolecular Heck reaction was described. The title compound was characterized by IR,1H NMR,13C NMR,elemental analysis,and MS.
关键词	TETRAALKYLAMMONIUM SALTS ANTOFINE phenanthrene-9-carboxyaldehyde synthesis Heck reaction
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:3370636
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/155268
专题	中国科学院金属研究所
作者单位	1.中国科学院金属研究所 2.Seoul Natl University, Coll Pharm, Seoul 151742, South Korea
推荐引用方式 GB/T 7714	Song Yanling,Zhai Xin,Sun Zhifeng,et al. Synthesis of 3-benzyloxy-6-methyl-7-methoxyphenanthrene-9-carboxaldehyde with utilize intramolecular Heck reaction as the key step[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2008,24(4):445-448.
APA	Song Yanling,Zhai Xin,Sun Zhifeng,Kim Sanghee,&Gong Ping.(2008).Synthesis of 3-benzyloxy-6-methyl-7-methoxyphenanthrene-9-carboxaldehyde with utilize intramolecular Heck reaction as the key step.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,24(4),445-448.
MLA	Song Yanling,et al."Synthesis of 3-benzyloxy-6-methyl-7-methoxyphenanthrene-9-carboxaldehyde with utilize intramolecular Heck reaction as the key step".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 24.4(2008):445-448.