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Lung tissue flap repairs esophagus defection with an inner chitosan tube stent
Alternative TitleLung tissue flap repairs esophagus defection with an inner chitosan tube stent
Chen Gang; Shi WenJun
2009
Source PublicationWORLD JOURNAL OF GASTROENTEROLOGY
ISSN1007-9327
Volume15Issue:12Pages:1512-1517
AbstractAIM: To repair the partial esophagus defect with a chitosan stent, a new esophageal prosthesis made of pulmonary tissue with vascular pedicle.
Other AbstractAIM:To repair the partial esophagus defect with a chitosan stent, a new esophageal prosthesis made of pulmonary tissue with vascular pedicle.METHODS: Fifteen Japanese big ear white rabbits were divided into experimental group (n=10) and control group (n=5). Esophagus defect in rabbits of experimental group was repaired using lung tissue flap with a chitosan tube stent, gross and histological appearance was observed at week 2,4 and 8 after operation, and barium sulphate X-ray screen was performed at week 10 after operation. Esophagus defect of rabbits in control group was repaired using lung tissue flap with no chitosan tube stent, gross and histological appearance was observed at week 2,4 and 8 after operation, and barium sulphate X-ray screen was performed at week 10 after operation.RESULTS: In the experimental group, 6 rabbits survived for over two weeks, the lung tissue flap healed esophageal defection, and squamous metaplasia occurred on the surface of lung tissue flap. At week 10 after operation, barium sulphate examination found that barium was fluent through the esophagus with no stricture or back stream, the creeping was good. In the control group, 4 rabbits survived for two weeks, the lung tissue flap healed esophageal defection with fibrous tissue hyperplasia, barium sulphate examination found that barium was fluent through the esophagus with a slight stricture or back stream, and the creeping was not good at week 10 after operation.CONCLUSION: Esophagus defect can be repaired using lung tissue flap with an inner chitosan tube stent.
KeywordGROWTH-FACTOR RECONSTRUCTION Lung Tissue flap Chitosan Stent Esophagus reconstruction
Indexed ByCSCD
Language英语
Funding Project[Science Foundation of Health Department]
CSCD IDCSCD:3614350
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/156654
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Chen Gang,Shi WenJun. Lung tissue flap repairs esophagus defection with an inner chitosan tube stent[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2009,15(12):1512-1517.
APA Chen Gang,&Shi WenJun.(2009).Lung tissue flap repairs esophagus defection with an inner chitosan tube stent.WORLD JOURNAL OF GASTROENTEROLOGY,15(12),1512-1517.
MLA Chen Gang,et al."Lung tissue flap repairs esophagus defection with an inner chitosan tube stent".WORLD JOURNAL OF GASTROENTEROLOGY 15.12(2009):1512-1517.
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