Comparative effects of percutaneous coronary intervention for infarct-related artery only or for both infarct- and non-infarct-related arteries in patients with ST-elevation myocardial infarction and multi-vessel disease

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	Comparative effects of percutaneous coronary intervention for infarct-related artery only or for both infarct- and non-infarct-related arteries in patients with ST-elevation myocardial infarction and multi-vessel disease
其他题名	Comparative effects of percutaneous coronary intervention for infarct-related artery only or for both infarct- and non-infarct- related arteries in patients with ST-elevation myocardial infarction and multi-vessel disease
	Han Yaling; Wang Bin; Wang Xiaozeng; Li Yi; Wang Shouli; Jing Quanmin; Wang Geng; Ma Yingyan; Luan Bo
	2008
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
卷号	121 期号:23 页码:2384-2387
摘要	Background Rapid recanalization of infarct-related artery (IRA) has become the major target during primary percutaneous coronary intervention (PCI) for patients with ST-elevation myocardial infarction (MI), but strategy for treatment of non-IRA lesions in this setting remains unclear. This study aimed to compare long-term effects between PCI for IRA only and that for both IRA and non-IRA in ST-elevation MI patients with multi-vessel disease.
其他摘要	Background Rapid recanalization of infarct-related artery (IRA) has become the major target during primary percutaneous coronary intervention (PCI) for patients with ST-elevation myocardial infarction (MI),but strategy for treatment of non-IRA lesions in this setting remains unclear.This study aimed to compare long-term effects between PCI for IRA only and that for both IRA and non-IRA in ST-elevation MI patients with multi-vessel disease.Methods A total of 242 eligible patients with ST-elevation MI and at least two diseased coronary arteries (luminal narrowing≥70%) undergoing primary PCI were included.Of them,149 patients underwent primary PCI for IRA only (group 1),and 93 received primary PCI for IRA followed by elective PCI for non-IRA 7 to 15 days after acute myocardial infarction (AMI) (group 2).Drug-eluting stents (DESs) were deployed in more than 90% of the patients.Results The two groups did not differ with respect to baseline clinical and angiographic characteristics.No significant differences were observed in 12-month clinical follow-up results regarding major adverse cardiac events (11.5% vs 15.1%,P>0.05) and target lesion revascularization (8.1% vs 7.6%,P>0.05) between the two groups.However,patients in group 1 had higher rates of recurrent angina (10.1% vs 2.1%,P<0.05) and depressed left ventricular ejection fraction evaluated by echocardiography (0.56±0.22 vs 0.63±0.25,P <0.05).Conclusion With the use of DESs,complete revascularization with elective PCI for non-IRA after primary PCI may exert a beneficial effect on long-term symptomatology and left ventricular function in patients with ST-elevation MI and multi-vessel disease.
关键词	DRUG-ELUTING STENTS MULTIVESSEL DISEASE CLINICAL-OUTCOMES BARE-METAL REVASCULARIZATION ANGIOPLASTY REPERFUSION IMMEDIATE STENOSIS CULPRIT multi-vessel disease percutaneous coronary intervention revascularization ST-elevation myocardial infarction
收录类别	CSCD
语种	英语
资助项目	[10th Five-Year Key Plan of PLA]
CSCD记录号	CSCD:3477129
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/156758
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Han Yaling,Wang Bin,Wang Xiaozeng,et al. Comparative effects of percutaneous coronary intervention for infarct-related artery only or for both infarct- and non-infarct-related arteries in patients with ST-elevation myocardial infarction and multi-vessel disease[J]. CHINESE MEDICAL JOURNAL,2008,121(23):2384-2387.
APA	Han Yaling.,Wang Bin.,Wang Xiaozeng.,Li Yi.,Wang Shouli.,...&Luan Bo.(2008).Comparative effects of percutaneous coronary intervention for infarct-related artery only or for both infarct- and non-infarct-related arteries in patients with ST-elevation myocardial infarction and multi-vessel disease.CHINESE MEDICAL JOURNAL,121(23),2384-2387.
MLA	Han Yaling,et al."Comparative effects of percutaneous coronary intervention for infarct-related artery only or for both infarct- and non-infarct-related arteries in patients with ST-elevation myocardial infarction and multi-vessel disease".CHINESE MEDICAL JOURNAL 121.23(2008):2384-2387.