IMR OpenIR
In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model
Wang, Haijian1; Kumazawa, Takashi1; Zhang, Ying1; Wang, Haiwei2,3; Ju, Dongying1,4,5
Corresponding AuthorJu, Dongying(dyju@sit.ac.jp)
2021-03-01
Source PublicationMATERIALS TODAY COMMUNICATIONS
ISSN2352-4928
Volume26Pages:12
AbstractA new type of Mg-rare earth (Ce, La) and the AZ31 alloy sheets were prepared by vertical twin-roll casting (TRC) technology under identical casting conditions, and their microstructural features, degradation behaviours and bone responses were investigated. The microstructural characterization showed that the Mg-RE (rare earth) exhibited a higher amorphous forming ability than the AZ31. Moreover, the results of electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization indicated that the Mg-RE sheets displayed a higher corrosion resistance compared with the AZ31 sheets. Additionally, the Ti, Mg-RE and AZ31 sheet implants were immobilized and implanted in a rat femur model to observe degradation behavior during 16 weeks. in vivo tests showed that no significant change in the femur surrounding the Ti group, which excluded the external factor that the new bone formation resulting from bone remodeling. Furthermore, the Mg-RE group induced more newly formed bones, which met the necessary conditions for the prevention of pathological fractures. Therefore, the novel Mg-RE alloy appear to hold a healing candidate as the biodegradable implant material.
KeywordMg-RE sheet In vivo Amorphous Degradable Bone response
Funding OrganizationHigh-Tech Research Center and Animal experiment Project
DOI10.1016/j.mtcomm.2020.101727
Indexed BySCI
Language英语
Funding ProjectHigh-Tech Research Center and Animal experiment Project[2019-5]
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, Multidisciplinary
WOS IDWOS:000634334200002
PublisherELSEVIER
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/161960
Collection中国科学院金属研究所
Corresponding AuthorJu, Dongying
Affiliation1.Saitama Inst Technol, Dept High Tech Res Ctr, Fusaiji 1690, Fukaya 3690293, Japan
2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
3.Univ Sci & Technol China Hefei, Sch Mat Sci & Engn, Hefei 230026, Peoples R China
4.Univ Sci & Technol Liaoning, Sch Mat & Met, Anshan 114051, Peoples R China
5.Ningbo Haizhi Inst Mat Ind Innovat, Ningbo 315000, Peoples R China
Recommended Citation
GB/T 7714
Wang, Haijian,Kumazawa, Takashi,Zhang, Ying,et al. In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model[J]. MATERIALS TODAY COMMUNICATIONS,2021,26:12.
APA Wang, Haijian,Kumazawa, Takashi,Zhang, Ying,Wang, Haiwei,&Ju, Dongying.(2021).In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model.MATERIALS TODAY COMMUNICATIONS,26,12.
MLA Wang, Haijian,et al."In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model".MATERIALS TODAY COMMUNICATIONS 26(2021):12.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, Haijian]'s Articles
[Kumazawa, Takashi]'s Articles
[Zhang, Ying]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, Haijian]'s Articles
[Kumazawa, Takashi]'s Articles
[Zhang, Ying]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, Haijian]'s Articles
[Kumazawa, Takashi]'s Articles
[Zhang, Ying]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.