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Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review
Chen, Junxiu1,2; Yang, Yang1,2; Etim, Iniobong P.3; Tan, Lili3; Yang, Ke3; Misra, R. D. K.4; Wang, Jianhua1,2; Su, Xuping1,2
Corresponding AuthorChen, Junxiu(czdxcjx@cczu.edu.cn) ; Yang, Ke(kyang@imr.ac.cn)
2021-10-01
Source PublicationMATERIALS
Volume14Issue:19Pages:15
AbstractThe wide application of magnesium alloys as biodegradable implant materials is limited because of their fast degradation rate. Hydroxyapatite (HA) coating can reduce the degradation rate of Mg alloys and improve the biological activity of Mg alloys, and has the ability of bone induction and bone conduction. The preparation of HA coating on the surface of degradable Mg alloys can improve the existing problems, to a certain extent. This paper reviewed different preparation methods of HA coatings on biodegradable Mg alloys, and their effects on magnesium alloys' degradation, biocompatibility, and osteogenic properties. However, no coating prepared can meet the above requirements. There was a lack of systematic research on the degradation of coating samples in vivo, and the osteogenic performance. Therefore, future research can focus on combining existing coating preparation technology and complementary advantages to develop new coating preparation techniques, to obtain more balanced coatings. Second, further study on the metabolic mechanism of HA-coated Mg alloys in vivo can help to predict its degradation behavior, and finally achieve controllable degradation, and further promote the study of the osteogenic effect of HA-coated Mg alloys in vivo.
Keywordmagnesium alloy hydroxyapatite coating degradation
Funding OrganizationNational Natural Science Foundation of China ; Changzhou Sci Tech Program ; Natural Science Foundation of the Jiangsu Higher Education Institutions of China ; Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP) ; Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
DOI10.3390/ma14195550
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[52001034] ; Changzhou Sci Tech Program[CJ20200078] ; Natural Science Foundation of the Jiangsu Higher Education Institutions of China[20KJB430013] ; Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP) ; Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
WOS Research AreaChemistry ; Materials Science ; Metallurgy & Metallurgical Engineering ; Physics
WOS SubjectChemistry, Physical ; Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering ; Physics, Applied ; Physics, Condensed Matter
WOS IDWOS:000709537700001
PublisherMDPI
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/167092
Collection中国科学院金属研究所
Corresponding AuthorChen, Junxiu; Yang, Ke
Affiliation1.Changzhou Univ, Key Lab Mat Surface Sci & Technol Jiangsu Prov, Changzhou 213164, Jiangsu, Peoples R China
2.Changzhou Univ, Jiangsu Collaborat Innovat Ctr Photovolta Sci & E, Changzhou 213164, Jiangsu, Peoples R China
3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
4.Univ Texas El Paso, Dept Met Mat & Biomed Engn, 500 West Univ Ave, El Paso, TX 79968 USA
Recommended Citation
GB/T 7714
Chen, Junxiu,Yang, Yang,Etim, Iniobong P.,et al. Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review[J]. MATERIALS,2021,14(19):15.
APA Chen, Junxiu.,Yang, Yang.,Etim, Iniobong P..,Tan, Lili.,Yang, Ke.,...&Su, Xuping.(2021).Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review.MATERIALS,14(19),15.
MLA Chen, Junxiu,et al."Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review".MATERIALS 14.19(2021):15.
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