| Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation | |
| Liu, Fei1; Wang, Xinyu2; Li, Shujun3; Liao, Yiheng1; Zhan, Xinxin4; Tao, Anqi1; Zheng, Fu5; Li, Huazhi5; Su, Yucheng6; Jiang, Jiuhui5; Li, Cuiying1 | |
| Corresponding Author | Jiang, Jiuhui(drjiangw@163.com) ; Li, Cuiying(Licuiying_67@163.com) |
| 2021-09-01 | |
| Source Publication | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
 |
| ISSN | 1550-7033 |
| Volume | 17Issue:9Pages:1812-1823 |
| Abstract | Ti-24Nb-4Zr-8Sn (Ti2448) alloys, with a relatively low elastic modulus and unique mechanical properties, are desirable materials for oral implantation. In the current study, a multifaceted strontium-incorporating nanotube coating was fabri-cated on a Ti2448 alloy (Ti2-NTSr) through anodization and hydrothermal procedures. In vitro, the Ti2-NTSr specimens demonstrated better osteogenic properties and more favorable osteoimmunomodulatory abilities. Moreover, macrophages on Ti2-NTSr specimens could improve the recruitment and osteogenic differentiation of osteoblasts. In vivo, dense clots with highly branched, thin fibrins and small pores existed on the Ti2-NTSr implant in the early stage after surgery. Analysis IP: 49.249.253.194 On: Mon, 25 Oct 2021 08:54 18 of the deposition of Ca and P elements, hard tissue slices and the bone-implant contact rate (BIC%) of the Ti2-NTSr Copyright: America Scientfic Publishers D lv d by g t implants also showed superior osseointegration. Taken together, these results demonstrate that the Ti2-NTSr coating may maximize the clinical outcomes of Ti2448 alloys for implantation applications. |
| Keyword | Ti-24Nb-4Zr-8Sn Osseointegration Osteoimmunomodulation Anodic Oxidation Strontium |
| Funding Organization | Touyan Project of Heilongjiang Province of China ; National Key Research and Development Program of China |
| DOI | 10.1166/jbn.2021.3160 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Touyan Project of Heilongjiang Province of China ; National Key Research and Development Program of China[2016YFC1102603] |
| WOS Research Area | Science & Technology - Other Topics ; Materials Science |
| WOS Subject | Nanoscience & Nanotechnology ; Materials Science, Biomaterials |
| WOS ID | WOS:000711456300002 |
| Publisher | AMER SCIENTIFIC PUBLISHERS |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/167147 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Jiang, Jiuhui; Li, Cuiying |
| Affiliation | 1.Peking Univ, Cent Lab, Sch & Hosp Stomatol, Beijing 100081, Peoples R China 2.Jiamusi Univ, Heilongjiang Key Lab Oral Biomed Mat & Clin Appli, Affiliated Stomatol Hosp, Jiamusi 154000, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Titanium Alloy Lab, Shenyang 110016, Peoples R China 4.Peking Univ, Dept Dent Mat, Sch & Hosp Stomatol, Beijing 100081, Peoples R China 5.Peking Univ, Dept Orthodont, Sch & Hosp Stomatol, Beijing 100081, Peoples R China 6.Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dent Implant Ctr, Beijing 100032, Peoples R China |
| Recommended Citation GB/T 7714 | Liu, Fei,Wang, Xinyu,Li, Shujun,et al. Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2021,17(9):1812-1823. |
| APA | Liu, Fei.,Wang, Xinyu.,Li, Shujun.,Liao, Yiheng.,Zhan, Xinxin.,...&Li, Cuiying.(2021).Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,17(9),1812-1823. |
| MLA | Liu, Fei,et al."Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 17.9(2021):1812-1823. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment