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Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation
Liu, Fei1; Wang, Xinyu2; Li, Shujun3; Liao, Yiheng1; Zhan, Xinxin4; Tao, Anqi1; Zheng, Fu5; Li, Huazhi5; Su, Yucheng6; Jiang, Jiuhui5; Li, Cuiying1
Corresponding AuthorJiang, Jiuhui(drjiangw@163.com) ; Li, Cuiying(Licuiying_67@163.com)
2021-09-01
Source PublicationJOURNAL OF BIOMEDICAL NANOTECHNOLOGY
ISSN1550-7033
Volume17Issue:9Pages:1812-1823
AbstractTi-24Nb-4Zr-8Sn (Ti2448) alloys, with a relatively low elastic modulus and unique mechanical properties, are desirable materials for oral implantation. In the current study, a multifaceted strontium-incorporating nanotube coating was fabri-cated on a Ti2448 alloy (Ti2-NTSr) through anodization and hydrothermal procedures. In vitro, the Ti2-NTSr specimens demonstrated better osteogenic properties and more favorable osteoimmunomodulatory abilities. Moreover, macrophages on Ti2-NTSr specimens could improve the recruitment and osteogenic differentiation of osteoblasts. In vivo, dense clots with highly branched, thin fibrins and small pores existed on the Ti2-NTSr implant in the early stage after surgery. Analysis IP: 49.249.253.194 On: Mon, 25 Oct 2021 08:54 18 of the deposition of Ca and P elements, hard tissue slices and the bone-implant contact rate (BIC%) of the Ti2-NTSr Copyright: America Scientfic Publishers D lv d by g t implants also showed superior osseointegration. Taken together, these results demonstrate that the Ti2-NTSr coating may maximize the clinical outcomes of Ti2448 alloys for implantation applications.
KeywordTi-24Nb-4Zr-8Sn Osseointegration Osteoimmunomodulation Anodic Oxidation Strontium
Funding OrganizationTouyan Project of Heilongjiang Province of China ; National Key Research and Development Program of China
DOI10.1166/jbn.2021.3160
Indexed BySCI
Language英语
Funding ProjectTouyan Project of Heilongjiang Province of China ; National Key Research and Development Program of China[2016YFC1102603]
WOS Research AreaScience & Technology - Other Topics ; Materials Science
WOS SubjectNanoscience & Nanotechnology ; Materials Science, Biomaterials
WOS IDWOS:000711456300002
PublisherAMER SCIENTIFIC PUBLISHERS
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/167147
Collection中国科学院金属研究所
Corresponding AuthorJiang, Jiuhui; Li, Cuiying
Affiliation1.Peking Univ, Cent Lab, Sch & Hosp Stomatol, Beijing 100081, Peoples R China
2.Jiamusi Univ, Heilongjiang Key Lab Oral Biomed Mat & Clin Appli, Affiliated Stomatol Hosp, Jiamusi 154000, Peoples R China
3.Chinese Acad Sci, Inst Met Res, Titanium Alloy Lab, Shenyang 110016, Peoples R China
4.Peking Univ, Dept Dent Mat, Sch & Hosp Stomatol, Beijing 100081, Peoples R China
5.Peking Univ, Dept Orthodont, Sch & Hosp Stomatol, Beijing 100081, Peoples R China
6.Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dent Implant Ctr, Beijing 100032, Peoples R China
Recommended Citation
GB/T 7714
Liu, Fei,Wang, Xinyu,Li, Shujun,et al. Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2021,17(9):1812-1823.
APA Liu, Fei.,Wang, Xinyu.,Li, Shujun.,Liao, Yiheng.,Zhan, Xinxin.,...&Li, Cuiying.(2021).Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,17(9),1812-1823.
MLA Liu, Fei,et al."Strontium-Loaded Nanotubes of Ti-24Nb-4Zr-8Sn Alloys for Biomedical Implantation".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 17.9(2021):1812-1823.
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