Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant

doi:10.1016/j.jmbbm.2021.104926

IMR OpenIR

	Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant
	Zhang, Shuyuan 1; Yu, Yachuan 2; Wang, Hai 1; Ren, Ling 1; Yang, Ke 1
通讯作者	Ren, Ling() ; Yang, Ke(kyang@imr.ac.cn)
	2022
发表期刊	JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
ISSN	1751-6161
卷号	125 页码:6
摘要	Cu-bearing titanium alloy has been proved to have excellent antibacterial properties, which can effectively reduce the incidence of infection caused by implantation. On the other hand, the addition of Cu in the titanium alloy can also significantly improve the strength of the alloy due to the dispersed precipitation of Ti2Cu compounds in matrix, which will enhance the biomechanical safety of Cu-bearing antibacterial titanium alloys. In this study, a Ti6Al4V5Cu antibacterial titanium alloy and the ordinary Ti6Al4V titanium alloy were used to make a variety of orthopedic trauma repair implants, including bone pin, bone screw and bone plate. Through the internationally accepted test methods, the mechanical properties such as tension, torsion and bending of the implants were studied, and the difference between the implants made of two materials was analyzed. The results showed that the tensile strength of Ti6Al4V5Cu pin was 25% higher than that of Ti6Al4V pin, the torsion strength of the screw was increased up to 89%, the static bending load of the plate was increased by 67-89%, and the maximum loading force of the plate after 1 million cycles of four point dynamic bending was increased by 41-91%. The above improvements should be attributed to the strengthening effect of Cu in the antibacterial titanium alloy, indicating that the Cu-bearing antibacterial titanium alloy implant possesses both advantages of reducing the bacterial infection and improving the biomechanical safety, and a broad clinical application prospects.
关键词	Cu-bearing antibacterial titanium alloy Orthopedic implant Mechanical properties
资助者	Natural Science Foundation of China ; National Key Research and Development Program of China
DOI	10.1016/j.jmbbm.2021.104926
收录类别	SCI
语种	英语
资助项目	Natural Science Foundation of China[51631009] ; Natural Science Foundation of China[31870954] ; National Key Research and Development Program of China[2018YFC1106600] ; National Key Research and Development Program of China[2016YFC1100600]
WOS研究方向	Engineering ; Materials Science
WOS类目	Engineering, Biomedical ; Materials Science, Biomaterials
WOS记录号	WOS:000717929700002
出版者	ELSEVIER
引用统计	被引频次：20[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/167436
专题	中国科学院金属研究所
通讯作者	Ren, Ling; Yang, Ke
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Suzhou Silvan Med Co Ltd, Suzhou 215000, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Shuyuan,Yu, Yachuan,Wang, Hai,et al. Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant[J]. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS,2022,125:6.
APA	Zhang, Shuyuan,Yu, Yachuan,Wang, Hai,Ren, Ling,&Yang, Ke.(2022).Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant.JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS,125,6.
MLA	Zhang, Shuyuan,et al."Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant".JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS 125(2022):6.