Involvement of striatal motoric subregions in familial frontotemporal dementia with parkinsonism harboring the C9orf72 repeat expansions

IMR OpenIR

	Involvement of striatal motoric subregions in familial frontotemporal dementia with parkinsonism harboring the C9orf72 repeat expansions
	Li Liu 1; Shuying Liu 1; Min Chu 1; Jingjuan Wang 1; Kexin Xie 1; Yue Cui 1; Jinghong Ma 1; Haitian Nan 1; Chunlei Cui 1; Hongwen Qiao 1; Pedro Rosa-Neto 3; Piu Chan 1; Liyong Wu 1
发表期刊	npj Parkinson's Disease
ISSN	2373-8057
卷号	8 期号:1
摘要	The chromosome 9 open reading frame 72 (C9ORF72) has been proposed as the causative gene of frontotemporal dementia with parkinsonism (FTDP), but its pathophysiological mechanism of parkinsonism is poorly understood. To explore the roles of striatal motor subdivisions in the pathogenesis of parkinsonism resulting from C9ORF72 repeat expansions in the FTDP, two patients with FTDP from one pedigree and seventeen healthy controls were enrolled. The participants received clinical interviews, physical examinations, genetic testing, 18 F-fluorodeoxyglucose PET 18 F-dihydrotetrabenazine PET
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/175291
专题	中国科学院金属研究所
作者单位	1.首都医科大学 2.中国科学院金属研究所 3.McGill Centre for Studies in Aging, Alzheimer’s Disease Research Unit 4.National Clinical Research Center for Geriatric Diseases
推荐引用方式 GB/T 7714	Li Liu,Shuying Liu,Min Chu,et al. Involvement of striatal motoric subregions in familial frontotemporal dementia with parkinsonism harboring the C9orf72 repeat expansions[J]. npj Parkinson's Disease,8(1).
APA	Li Liu.,Shuying Liu.,Min Chu.,Jingjuan Wang.,Kexin Xie.,...&Liyong Wu.
MLA	Li Liu,et al."Involvement of striatal motoric subregions in familial frontotemporal dementia with parkinsonism harboring the C9orf72 repeat expansions".npj Parkinson's Disease 8.1