Nanozymes with atomically dispersed metal centers: Structure-activity relationships and biomedical applications

doi:10.1016/j.cej.2022.139411

IMR OpenIR

	Nanozymes with atomically dispersed metal centers: Structure-activity relationships and biomedical applications
	Meng, Fanchi 1,2; Zhu, Pengbo 1; Yang, Lini 1; Xia, Lixin 1; Liu, Hongyang 2
通讯作者	Yang, Lini(lnyang@lnu.edu.cn) ; Liu, Hongyang(liuhy@imr.ac.cn)
	2023-01-15
发表期刊	CHEMICAL ENGINEERING JOURNAL
ISSN	1385-8947
卷号	452 页码:11
摘要	Nanozymes has become a research hotspot in biomedical field because of its great enzyme-like catalytic per-formance and biological characteristics. As a potential substitute for natural enzyme, nanozymes have the ad-vantages of low cost, strong catalytic performance and good stability. The discovery of nanozymes with atomically dispersed metal centers has attracted the focus of nanozymes research to the atomic level. Compared with nanoparticles nanozymes, the single-atom nanozymes with atomically dispersed single-metal sites and the atomically dispersed cluster nanozymes with atomically dispersed multi-metal sites have higher atomic utili-zation rate and thus have stronger catalytic performance. In addition, atomically dispersed active centers are beneficial to the regulation of catalytic performance and the study of structure-activity relationship. At present, the research on nanozymes with atomically dispersed metal centers has achieved many important results and showed considerable application value in biomedical field. This review presents the research progress of nanozymes with atomically dispersed metal centers and systematically summarizes their structure-activity re-lationships and biomedical applications. Finally, we discuss the current opportunities and challenges of nano-zymes with atomically dispersed metal centers.
关键词	Atomically dispersed Metal centers Nanozymes Structure-activity relationship Biomedicine applications
资助者	National Key R & D Program of China ; National Natural Science Foundation of China ; Liaoning Revitalization Talents Program ; Scientific Research Fund of Liaoning Province ; Shenyang Natural Sci- ence Foundation of China
DOI	10.1016/j.cej.2022.139411
收录类别	SCI
语种	英语
资助项目	National Key R & D Program of China ; National Natural Science Foundation of China ; Liaoning Revitalization Talents Program ; Scientific Research Fund of Liaoning Province ; Shenyang Natural Sci- ence Foundation of China ; [2021YFA1502802] ; [21773101] ; [92145301] ; [U21B2092] ; [21961160722] ; [91845201] ; [22072162] ; [XLYC1807151] ; [LZD201601] ; [LT2017010] ; [20170540409] ; [F16-103-4-00]
WOS研究方向	Engineering
WOS类目	Engineering, Environmental ; Engineering, Chemical
WOS记录号	WOS:000864031000002
出版者	ELSEVIER SCIENCE SA
引用统计	被引频次：40[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/176041
专题	中国科学院金属研究所
通讯作者	Yang, Lini; Liu, Hongyang
作者单位	1.Liaoning Univ, Dept Chem, 66 Chongshan Rd, Shenyang 110036, Liaoning, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Meng, Fanchi,Zhu, Pengbo,Yang, Lini,et al. Nanozymes with atomically dispersed metal centers: Structure-activity relationships and biomedical applications[J]. CHEMICAL ENGINEERING JOURNAL,2023,452:11.
APA	Meng, Fanchi,Zhu, Pengbo,Yang, Lini,Xia, Lixin,&Liu, Hongyang.(2023).Nanozymes with atomically dispersed metal centers: Structure-activity relationships and biomedical applications.CHEMICAL ENGINEERING JOURNAL,452,11.
MLA	Meng, Fanchi,et al."Nanozymes with atomically dispersed metal centers: Structure-activity relationships and biomedical applications".CHEMICAL ENGINEERING JOURNAL 452(2023):11.