The Effect of Plasma Treatment on the Mechanical and Biological Properties of Polyurethane Artificial Blood Vessel

doi:10.3390/ma16227231

IMR OpenIR

	The Effect of Plasma Treatment on the Mechanical and Biological Properties of Polyurethane Artificial Blood Vessel
	Ding, Cheng 1,2; Ma, Jing 2; Teng, Yingxue 1; Chen, Shanshan 2
通讯作者	Teng, Yingxue(tengyingxue_2007@163.com) ; Chen, Shanshan(sschen@imr.ac.cn)
	2023-11-01
发表期刊	MATERIALS
卷号	16 期号:22 页码:14
摘要	In recent years, the incidence of cardiovascular disease has increased annually, and the demand for artificial blood vessels has been increasing. Due to the formation of thrombosis and stenosis after implantation, the application of many materials in the human body has been inhibited. Therefore, the choice of surface modification process is very important. In this paper, small-diameter polyurethane artificial blood vessels were prepared through electrospinning, and their surfaces were treated with plasma to improve their biological properties. The samples before and after plasma treatment were characterized by SEM, contact angle, XPS, and tensile testing; meanwhile, the cell compatibility and blood compatibility were evaluated. The results show that there are no significant changes to the fiber morphology or diameter distribution on the surface of the sample before and after plasma treatment. Plasma treatment can increase the proportion of oxygen-containing functional groups on the surface of the sample and improve its wettability, thereby increasing the infiltration ability of cells and promoting cell proliferation. Plasma treatment can reduce the risk of hemolysis, and does not cause platelet adhesion. Due to the etching effect of plasma, the mechanical properties of the samples decreased with the extension of plasma treatment time, which should be used as a basis to balance the mechanical property and biological property of artificial blood vessels. But on the whole, plasma treatment has positive significance for improving the comprehensive performance of samples.
关键词	polyurethane artificial blood vessels electrospinning plasma treatment biocompatibility mechanical properties
资助者	National Key Research and Development Program of China
DOI	10.3390/ma16227231
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China[2023YFB3810100]
WOS研究方向	Chemistry ; Materials Science ; Metallurgy & Metallurgical Engineering ; Physics
WOS类目	Chemistry, Physical ; Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering ; Physics, Applied ; Physics, Condensed Matter
WOS记录号	WOS:001118159400001
出版者	MDPI
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/177313
专题	中国科学院金属研究所
通讯作者	Teng, Yingxue; Chen, Shanshan
作者单位	1.Univ Sci & Technol Liaoning, Sch Mat & Met, Anshan 114051, Peoples R China 2.Chinese Acad Sci, Shi Changxu Innovat Ctr Adv Mat, Inst Met Res, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Ding, Cheng,Ma, Jing,Teng, Yingxue,et al. The Effect of Plasma Treatment on the Mechanical and Biological Properties of Polyurethane Artificial Blood Vessel[J]. MATERIALS,2023,16(22):14.
APA	Ding, Cheng,Ma, Jing,Teng, Yingxue,&Chen, Shanshan.(2023).The Effect of Plasma Treatment on the Mechanical and Biological Properties of Polyurethane Artificial Blood Vessel.MATERIALS,16(22),14.
MLA	Ding, Cheng,et al."The Effect of Plasma Treatment on the Mechanical and Biological Properties of Polyurethane Artificial Blood Vessel".MATERIALS 16.22(2023):14.