Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip

doi:10.3390/jfb14100501

IMR OpenIR

	Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip
	Zhang, Hongxu 1,2; Gao, Ming 2; Tian, Xiaoying 2; Cao, Dali 1; Tan, Lili 2
通讯作者	Cao, Dali(caodali2008@163.com) ; Tan, Lili(lltan@imr.ac.cn)
	2023-10-01
发表期刊	JOURNAL OF FUNCTIONAL BIOMATERIALS
卷号	14 期号:10 页码:15
摘要	The Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this study, the process of clamping blood vessels with a biodegradable Mg alloy (Mg-Zn-Nd-Zr and Mg-Zn-Nd) general V-type vascular clip was simulated by finite element simulation software (Abaqus). A new type of vascular clip, the P-type vascular clip, was analyzed and investigated through simulation. The differences between Mg alloy vascular clips of V-type and P-type were analyzed by finite element simulation. In addition, the effects of Zr element on the mechanical properties and corrosion resistance of P-type vascular clips were also investigated to improve the mechanical stability. The results show that during the V-type vascular clip closure of Mg-Zn-Nd-Zr alloy, this clip has some problems, such as uneven distribution of blood vessel stress, crevices in blood vessels and stress concentration. The improved P-type vascular clip has uniform closure, and there is no gap in the blood vessel, which can effectively avoid stress concentration. The improved P-type vascular clip is well closed and can effectively avoid stress concentration. The corrosion resistance of the Mg-Zn-Nd-Zr alloy P-type clip was better than that of the Mg-Zn-Nd alloy P-type clip (degradation rate of 2.02 mm/y and 2.61 mm/y on the 7th day, respectively). Mg-Zn-Nd-Zr alloy The P-type vascular clip remained closed even on the 7th day, which could meet the requirements of clinical application.
关键词	finite element modelling biodegradable Mg alloy vascular clip structural design corrosion resistance
资助者	National Key Research and Development Program of China ; National Natural Science Foundation of China ; STS program ; DongGuan Innovative Research Team Program, Basic applied research program of Liaoning Province of China
DOI	10.3390/jfb14100501
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China[2020YFC1107501] ; National Natural Science Foundation of China[51971222] ; National Natural Science Foundation of China[2022020347-JH2/1013] ; STS program[52201302] ; DongGuan Innovative Research Team Program, Basic applied research program of Liaoning Province of China[20201600200042]
WOS研究方向	Engineering ; Materials Science
WOS类目	Engineering, Biomedical ; Materials Science, Biomaterials
WOS记录号	WOS:001095427100001
出版者	MDPI
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/177554
专题	中国科学院金属研究所
通讯作者	Cao, Dali; Tan, Lili
作者单位	1.Shenyang Univ Chem Technol, Mat Sci & Engn, 11 St Shenyang Econ & Technol Dev Area, Shenyang 110142, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Hongxu,Gao, Ming,Tian, Xiaoying,et al. Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip[J]. JOURNAL OF FUNCTIONAL BIOMATERIALS,2023,14(10):15.
APA	Zhang, Hongxu,Gao, Ming,Tian, Xiaoying,Cao, Dali,&Tan, Lili.(2023).Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip.JOURNAL OF FUNCTIONAL BIOMATERIALS,14(10),15.
MLA	Zhang, Hongxu,et al."Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip".JOURNAL OF FUNCTIONAL BIOMATERIALS 14.10(2023):15.