Preparation and biomedical applications of artificial cells

doi:10.1016/j.mtbio.2023.100877

IMR OpenIR

	Preparation and biomedical applications of artificial cells
	Xu, Qian 1,2; Zhang, Zeping 2,3; Lui, Pauline Po Yee 4; Lu, Liang 2,3; Li, Xiaowu 1; Zhang, Xing 2,3
通讯作者	Li, Xiaowu(xwli@mail.neu.edu.cn) ; Zhang, Xing(xingzhang@imr.ac.cn)
	2023-12-01
发表期刊	MATERIALS TODAY BIO
ISSN	2590-0064
卷号	23 页码:14
摘要	Artificial cells have received much attention in recent years as cell mimics with typical biological functions that can be adapted for therapeutic and diagnostic applications, as well as having an unlimited supply. Although remarkable progress has been made to construct complex multifunctional artificial cells, there are still significant differences between artificial cells and natural cells. It is therefore important to understand the techniques and challenges for the fabrication of artificial cells and their applications for further technological advancement. The key concepts of top-down and bottom-up methods for preparing artificial cells are summarized, and the advantages and disadvantages of the bottom-up methods are compared and critically discussed in this review. Potential applications of artificial cells as drug carriers (microcapsules), as signaling regulators for coordinating cellular communication and as bioreactors for biomolecule fabrication, are further discussed. The challenges and future trends for the development of artificial cells simulating the real activities of natural cells are finally described.
关键词	Artificial cells Bottom-up approach Microcapsules Cellular communication Bioreactors
资助者	National Natural Science Foundation of China ; Liao Ning Revitalization Talents Program
DOI	10.1016/j.mtbio.2023.100877
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[52273278] ; Liao Ning Revitalization Talents Program[XLYC2007112]
WOS研究方向	Engineering ; Materials Science
WOS类目	Engineering, Biomedical ; Materials Science, Biomaterials
WOS记录号	WOS:001128798900001
出版者	ELSEVIER
引用统计	被引频次：15[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/183143
专题	中国科学院金属研究所
通讯作者	Li, Xiaowu; Zhang, Xing
作者单位	1.Northeastern Univ, Key Lab Anisotropy & Texture Mat, Dept Mat Phys & Chem, Sch Mat Sci & Engn,Minist Educ, Shenyang 110819, Liaoning, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 3.Univ Sci & Technol China, Dept Mat Sci & Engn, Hefei 230026, Anhui, Peoples R China 4.Chinese Univ Hong Kong, Dept Orthopaed & Traumatol, Hong Kong 999077, Peoples R China
推荐引用方式 GB/T 7714	Xu, Qian,Zhang, Zeping,Lui, Pauline Po Yee,et al. Preparation and biomedical applications of artificial cells[J]. MATERIALS TODAY BIO,2023,23:14.
APA	Xu, Qian,Zhang, Zeping,Lui, Pauline Po Yee,Lu, Liang,Li, Xiaowu,&Zhang, Xing.(2023).Preparation and biomedical applications of artificial cells.MATERIALS TODAY BIO,23,14.
MLA	Xu, Qian,et al."Preparation and biomedical applications of artificial cells".MATERIALS TODAY BIO 23(2023):14.