The mechanical properties and bioactivity of Ti-Mg composites as orthopedic implants: A pilot study

doi:10.1016/j.jmrt.2023.12.068

IMR OpenIR

	The mechanical properties and bioactivity of Ti-Mg composites as orthopedic implants: A pilot study
	Miao, Lei 1; Gao, Ming 2; Chen, Siying 1; Wang, Jinhe 2; Zhang, Haifeng 2; Tan, Lili 2; Pan, Yaping 1
通讯作者	Tan, Lili(lltan@imr.ac.cn) ; Pan, Yaping(yppan@cmu.edu.cn)
	2024
发表期刊	JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
ISSN	2238-7854
卷号	28 页码:1074-1083
摘要	Stress shielding effects and bioinertia are two main problems of titanium alloy orthopedic implants, which are commonly used in clinical therapy. By adjusting the porosity of the Ti alloy, the stress shielding effects can be avoided and the strength of the titanium alloy is also significantly decreased. To improve the mechanical property and bioactivity, Ti-Mg composites were fabricated by pressureless infiltration and 3D printed. Excellent mechanical properties, biocompatibility and bioactivity of the Ti-Mg composites were demonstrated by in vitro and in vivo results. The ultimate compressive strength and compressive yield strength could be increased to 292.5 +/- 10.0 MPa and 27.9 % 220.0 +/- 11.5 MPa, respectively. Furthermore, the bioactivity of Ti-Mg composites was also significantly improved due to the release of Mg ions during the degradation process, which can promote osteoblast adhesion and differentiation.
关键词	Ti-Mg composites Mechanical properties Corrosion Bioactivity
资助者	National Key Research and Development Program of China ; National Natural Science Foundation of China ; STS program ; DongGuan Innovative Research Team Program and Basic applied research program of Liaoning Province of China
DOI	10.1016/j.jmrt.2023.12.068
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China[2020YFC1107501] ; National Natural Science Foundation of China[82170969] ; National Natural Science Foundation of China[51971222] ; National Natural Science Foundation of China[52201302] ; STS program[20201600200042] ; DongGuan Innovative Research Team Program and Basic applied research program of Liaoning Province of China[2022020347-JH2/1013]
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
WOS类目	Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS记录号	WOS:001140185900001
出版者	ELSEVIER
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/183563
专题	中国科学院金属研究所
通讯作者	Tan, Lili; Pan, Yaping
作者单位	1.China Med Univ, Sch & Hosp Stomatol, Dept Periodont, Liaoning Prov Key Lab Oral Dis, Shenyang 110000, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Miao, Lei,Gao, Ming,Chen, Siying,et al. The mechanical properties and bioactivity of Ti-Mg composites as orthopedic implants: A pilot study[J]. JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T,2024,28:1074-1083.
APA	Miao, Lei.,Gao, Ming.,Chen, Siying.,Wang, Jinhe.,Zhang, Haifeng.,...&Pan, Yaping.(2024).The mechanical properties and bioactivity of Ti-Mg composites as orthopedic implants: A pilot study.JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T,28,1074-1083.
MLA	Miao, Lei,et al."The mechanical properties and bioactivity of Ti-Mg composites as orthopedic implants: A pilot study".JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T 28(2024):1074-1083.