| Advances and prospects of 3D printed antibacterial bone implants: A systematic review | |
| Liu, Xin1; Lu, Sihan1; Wang, Tianlin1; Wang, Xiaohong1; Yang, Ke2; Yang, Huazhe1 | |
| 通讯作者 | Wang, Xiaohong(wangxiaohong@cmu.edu.cn) ; Yang, Ke(kyang@imr.ac.cn) ; Yang, Huazhe(hzyang@cmu.edu.cn) |
| 2024-11-20 | |
| 发表期刊 | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
 |
| ISSN | 1005-0302 |
| 卷号 | 200页码:227-242 |
| 摘要 | Bone defect is a serious problem for clinical orthopedics, and the construction of bone implants with ideal size, shape, structure and demanded biofunctions, etc., is of great importance for bone repairs. Especially, the endowment of implants with antibacterial activities is a promising strategy for the potential occurrence of infections during and/or after bone graft surgery. Three-dimensional (3D) printing, a hot technological strategy in tissue engineering, is increasingly applied in manufacturing various personalized, controlled and precise bone implants. However, significant challenges remain in overcoming infections. In this systematic review, different 3D-printed antibacterial bone implants are critically reviewed, and a general summary of the latest researches is systemically expounded, in which different antibacterial agents are involved: (i) inorganic; (ii) organic micromolecule; (iii) organic macromolecule; (iv) "functionassist" materials. Moreover, designments of printing processes, loading methods of antibacterial agents, functional treatments of bone implants, and related antibacterial mechanisms are also discussed. Overall, it is demonstrated that antibacterial 3D-printed bone implants exhibit excellent bone regeneration and bacterial resistance. Especially, the limitations and future expectations on the strategies and the development of the "programmed" antibacterial implants, are highlighted. This systematic review can provide a comprehensive understanding and insightful guidance for further exploring promising antimicrobial bone implants. (c) 2024 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology. |
| 关键词 | 3D printing Bone Implants Infection Antibacterial |
| 资助者 | Foundation of the Education Department of Liaoning Province in China ; Key Research & Development Project of Liaoning Province ; National Natural Sci-ence Foundation of China ; National Key Research and Development Program of China |
| DOI | 10.1016/j.jmst.2024.02.040 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | Foundation of the Education Department of Liaoning Province in China[JYTMS20230134] ; Key Research & Development Project of Liaoning Province[2018225082] ; National Natural Sci-ence Foundation of China[81500897] ; National Natural Sci-ence Foundation of China[81571832] ; National Key Research and Development Program of China[2022YFC2406003] |
| WOS研究方向 | Materials Science ; Metallurgy & Metallurgical Engineering |
| WOS类目 | Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering |
| WOS记录号 | WOS:001238117200001 |
| 出版者 | JOURNAL MATER SCI TECHNOL |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.imr.ac.cn/handle/321006/186995 |
| 专题 | 中国科学院金属研究所 |
| 通讯作者 | Wang, Xiaohong; Yang, Ke; Yang, Huazhe |
| 作者单位 | 1.China Med Univ CMU, Shenyang 110122, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Xin,Lu, Sihan,Wang, Tianlin,et al. Advances and prospects of 3D printed antibacterial bone implants: A systematic review[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2024,200:227-242. |
| APA | Liu, Xin,Lu, Sihan,Wang, Tianlin,Wang, Xiaohong,Yang, Ke,&Yang, Huazhe.(2024).Advances and prospects of 3D printed antibacterial bone implants: A systematic review.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,200,227-242. |
| MLA | Liu, Xin,et al."Advances and prospects of 3D printed antibacterial bone implants: A systematic review".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 200(2024):227-242. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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