Robust Chiral Metal-Organic Framework Coatings for Self-Activating and Sustainable Biofouling Mitigation

doi:10.1002/adma.202407409

IMR OpenIR

	Robust Chiral Metal-Organic Framework Coatings for Self-Activating and Sustainable Biofouling Mitigation
	Yu, Zhiqun 1; Li, Xiangyu 1; Wang, Zhengxing 2; Fan, Yongqiang 2; Zhao, Wenjie 3; Li, Dianzhong 4; Xu, Dake 1; Gu, Tingyue 5; Wang, Fuhui 1
通讯作者	Li, Xiangyu(lixiangyu@mail.neu.edu.cn) ; Xu, Dake(xudake@mail.neu.edu.cn)
	2024-09-05
发表期刊	ADVANCED MATERIALS
ISSN	0935-9648
页码	14
摘要	Surface coatings are designed to mitigate pervasive biofouling herald, a new era of surface protection in complex biological environments. However, existing strategies are plagued by persistent and recurrent biofilm attachment, despite the use of bactericidal agents. Herein, a chiral metal-organic framework (MOF)-based coating with conformal microstructures to enable a new anti-biofouling mode that involves spontaneous biofilm disassembly followed by bacterial eradication is developed. A facile and universal metal-polyphenol network (MPN) is designed to robustly anchor the MOF nanoarmor of biocidal Cu2+ ions and anti-biofilm d-amino acid ligands to a variety of substrates across different material categories and surface topologies. Incorporating a diverse array of chiral amino acids endows the resultant coatings with widespread signals for biofilm dispersal, facilitating copper-catalyzed chemodynamic reactions and inherent mechano-bactericidal activities. This synergistic mechanism yields unprecedented anti-biofouling efficacy elucidated by RNA-sequencing transcriptomics analysis, enhancing broad-spectrum antibacterial activities, preventing biofilm formation, and destroying mature biofilms. Additionally, the chelation-directed amorphous/crystalline coatings can activate photoluminescent properties to inhibit the settlement of microalgae biofilms. This study provides a distinctive perspective on chirality-enhanced antimicrobial behaviors and pioneers a rational pathway toward developing next-generation anti-biofouling coatings for diverse applications.
关键词	metal-polyphenol network metal-organic framework d-amino acid robust nanostructures synergistic anti-biofouling
资助者	National Science Fund for Distinguished Young Scholars ; National Key Research and Development Program of China ; National Natural Science Foundation of China ; National Postdoctoral Program for Innovative Talents ; China Postdoctoral Science Foundation ; Liaoning Provincial Natural Science Foundation of China ; Open Research Fund of Key Laboratory of Advanced Marine Materials ; State Key Laboratory of Marine Coatings Funded Project ; Fundamental Research Funds for the Central Universities
DOI	10.1002/adma.202407409
收录类别	SCI
语种	英语
资助项目	National Science Fund for Distinguished Young Scholars[52425112] ; National Key Research and Development Program of China[2022YFB3808800] ; National Natural Science Foundation of China[52301081] ; National Postdoctoral Program for Innovative Talents[BX20220059] ; China Postdoctoral Science Foundation[2022M720677] ; Liaoning Provincial Natural Science Foundation of China[2023-BS-052] ; Open Research Fund of Key Laboratory of Advanced Marine Materials[2024K04] ; State Key Laboratory of Marine Coatings Funded Project[2024020800027] ; Fundamental Research Funds for the Central Universities[N2302015]
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS记录号	WOS:001306757200001
出版者	WILEY-V C H VERLAG GMBH
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/189661
专题	中国科学院金属研究所
通讯作者	Li, Xiangyu; Xu, Dake
作者单位	1.Northeastern Univ, Corros & Protect Ctr, Shenyang 110819, Peoples R China 2.Northeastern Univ, Coll Life & Hlth Sci, Shenyang 110819, Peoples R China 3.Chinese Acad Sci, Ningbo Inst Mat Technol & Engn, Key Lab Adv Marine Mat, Ningbo 315201, Peoples R China 4.Inst Met Sci & Technol, Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Shenyang 110016, Peoples R China 5.Ohio Univ, Dept Chem & Biomol Engn, Edison Biotechnol Inst, Athens, OH 45701 USA
推荐引用方式 GB/T 7714	Yu, Zhiqun,Li, Xiangyu,Wang, Zhengxing,et al. Robust Chiral Metal-Organic Framework Coatings for Self-Activating and Sustainable Biofouling Mitigation[J]. ADVANCED MATERIALS,2024:14.
APA	Yu, Zhiqun.,Li, Xiangyu.,Wang, Zhengxing.,Fan, Yongqiang.,Zhao, Wenjie.,...&Wang, Fuhui.(2024).Robust Chiral Metal-Organic Framework Coatings for Self-Activating and Sustainable Biofouling Mitigation.ADVANCED MATERIALS,14.
MLA	Yu, Zhiqun,et al."Robust Chiral Metal-Organic Framework Coatings for Self-Activating and Sustainable Biofouling Mitigation".ADVANCED MATERIALS (2024):14.