Highly efficient layered Ir sub-nanoclusters for antibacterial application

doi:10.26599/NR.2025.94907234

IMR OpenIR

	Highly efficient layered Ir sub-nanoclusters for antibacterial application
	Yang, Lini 1; Zhu, Pengbo 1,2; Li, Tao 1; Jiao, Yueyue 3,4; Cai, Xiangbin 5,6; Liang, Jialan 1; Zhang, Hexin 1; Wang, Ning 5,6; Chen, Xiaowen 7; Liu, Hongyang 7
通讯作者	Yang, Lini(lnyang@lnu.edu.cn) ; Chen, Xiaowen(xwchen18s@imr.ac.cn) ; Liu, Hongyang(liuhy@imr.ac.cn)
	2025-03-01
发表期刊	NANO RESEARCH
ISSN	1998-0124
卷号	18 期号:3 页码:8
摘要	Atomically dispersed nanozymes have garnered immense attention within the biomedical field, while precisely designing these nanozymes and elucidating their intricate structure- performance relationships of their structures and antibacterial performance remain the formidable challenges. Herein, we fabricated defect-rich graphene supported layered Ir cluster nanozymes for antibacterial applications. Steady-state kinetic experiments revealed that the layered Ir clusters exhibited the higher catalytic efficiency of 1.16 mM-1s-1 with 3,3',5,5'-tetramethylbenzidine (TMB) and 0.18 mM-1s-1 with H2O2, compared to Ir nanoparticle (0.55 and 0.1 mM-1s-1) and the atomically dispersed Ir single-atom nanozyme (SAzyme) (0.3 and 0.039 mM-1s-1) and other previously reported single-atom nanozymes. Moreover, both experimental results and density functional theory studies disclosed that the layered Ir clusters exhibited the enhanced ability to facilitate the conversion of hydrogen peroxide into hydroxyl free radicals, signifying the higher catalytic efficiency than that on Ir nanoparticles and Ir single-atoms. Notably, the Ir cluster nanozyme with robust peroxidase-like activity had 100% antimicrobial rate against E. coli and S. aureus, underscoring its potential applications in antibacterial fields.
关键词	defect-rich graphene Ir catalyst sub-nanocluster peroxidase-like activity antibacterial application
资助者	National Natural Science Foundation of China ; International Partnership Program of Chinese Academy of Sciences ; Shenyang Young Talents Program ; Natural Science Foundation of Liaoning Province ; Liaoning BaiQianWan Talents Program and Guangxi Collaborative Innovation Centre of Structure and Property for New Energy and Materials, Science Research, Technology Development Project of Guilin ; Shanghai Synchrotron Radiation Facility (SSRF)
DOI	10.26599/NR.2025.94907234
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[U21B2092] ; National Natural Science Foundation of China[22402210] ; National Natural Science Foundation of China[22202213] ; National Natural Science Foundation of China[21961160722] ; International Partnership Program of Chinese Academy of Sciences ; Shenyang Young Talents Program ; Natural Science Foundation of Liaoning Province ; Liaoning BaiQianWan Talents Program and Guangxi Collaborative Innovation Centre of Structure and Property for New Energy and Materials, Science Research, Technology Development Project of Guilin[20210102-4] ; Shanghai Synchrotron Radiation Facility (SSRF) ; [22072162] ; [172GJHZ2022028MI] ; [RC220155] ; [2024-MS-05]
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
WOS记录号	WOS:001447333100001
出版者	TSINGHUA UNIV PRESS
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/192035
专题	中国科学院金属研究所
通讯作者	Yang, Lini; Chen, Xiaowen; Liu, Hongyang
作者单位	1.Liaoning Univ, Dept Chem, 66 Congshan Rd, Shenyang 110036, Peoples R China 2.Liaoning Dandong Ecol Environm Monitoring Ctr, Dandong, Peoples R China 3.Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, Taiyuan 030001, Peoples R China 4.Synfuels China Co Ltd, Natl Energy Ctr Coal Clean Fuel, Beijing 100871, Peoples R China 5.Hong Kong Univ Sci & Technol, Dept Phys, Ctr Quantum Mat, Kowloon, Clear Water Bay, Hong Kong, Peoples R China 6.Hong Kong Univ Sci & Technol, Ctr Quantum Mat, Kowloon, Clear Water Bay, Hong Kong, Peoples R China 7.Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Yang, Lini,Zhu, Pengbo,Li, Tao,et al. Highly efficient layered Ir sub-nanoclusters for antibacterial application[J]. NANO RESEARCH,2025,18(3):8.
APA	Yang, Lini.,Zhu, Pengbo.,Li, Tao.,Jiao, Yueyue.,Cai, Xiangbin.,...&Liu, Hongyang.(2025).Highly efficient layered Ir sub-nanoclusters for antibacterial application.NANO RESEARCH,18(3),8.
MLA	Yang, Lini,et al."Highly efficient layered Ir sub-nanoclusters for antibacterial application".NANO RESEARCH 18.3(2025):8.