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Exendin-4治疗2型糖尿病的研究进展
周琼; 凤姣
2010-11-15
Source Publication复旦学报(医学版)
Issue6Pages:738-741
Abstract近年来,Exendin-4成为2型糖尿病治疗研究的热点。它是一种含有39肽的氨基酸,与胰高血糖素样肽1(glucagon-like peptide 1,GLP-1)具有相似的降糖机制,属于GLP-1受体激动剂。Exendin-4在血糖浓度较高的情况下能促进胰岛素分泌,不但可以使初治2型糖尿病患者血糖正常,而且对于使用磺酰脲类和双胍类药物治疗失效者也有降血糖作用。本文就Exendin-4的国内外研究进展、作用机制以及临床药效学性质和安全性评价做一综述。
description.department复旦大学生命科学学院发育所;中国科学院金属研究所;
KeywordExendin-4 2型糖尿病 Glp-1 机制
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/23609
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
周琼,凤姣. Exendin-4治疗2型糖尿病的研究进展[J]. 复旦学报(医学版),2010(6):738-741.
APA 周琼,&凤姣.(2010).Exendin-4治疗2型糖尿病的研究进展.复旦学报(医学版)(6),738-741.
MLA 周琼,et al."Exendin-4治疗2型糖尿病的研究进展".复旦学报(医学版) .6(2010):738-741.
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