In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment

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	In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment
	X. Han; H. C. Liu; D. S. Wang; S. J. Li; R. Yang; X. J. Tao; X. H. Jiang
	2011
发表期刊	Journal of Materials Science & Technology
ISSN	1005-0302
卷号	27 期号:4 页码:317-324
摘要	The purpose of this study was to test the hypothesis that the combination of micro-arc oxidation and alkali heatment (MAH) would improve the cytocompatibility of a newly designed Ti-24Nb-4Zr-8Sn alloy. In this study, commercially pure titanium (cp Ti) and Ti-24Nb-4Zr-8Sn were used. Surface modification of Ti-24Nb-4Zr-8Sn by a two-step treatment of micro-arc oxidation (MAO) and alkali heatment was reported. Surface characterizations were performed by scanning electron microscopy (SEM), thin film X-ray diffraction (TF-XRD) and X-ray photoelectron spectroscopy (XPS). The MAH layer consisted of finer crystals and possessed a higher degree of crystallity and stability than the MAO layer. A biocompatibility study on treated and untreated Ti-24Nb-4Zr-8Sn in comparison with cp Ti was carried out to investigate the effect of the different surfaces on the bone integration property in vitro. The cellular assays revealed that the MAO and MAH layer favored the initial adhesion of MC3T3-E1 cells and that the growth rate of MC3T3-E1 cells on MAH layer was significantly higher than that on the conventional MAO-treated layer after 3-day and 5-day incubation, demonstrating the greater potential of the hybrid treatment of micro-arc oxidation followed with alkali heatment as a novel surface modification method for implanting materials.
部门归属	[han, xue; liu, hongchen; wang, dongsheng] gen hosp chinese peoples liberat army, inst dent, beijing 100853, peoples r china. [han, xue] gen hosp shenyang mil reg, dept stomatol, shenyang 110015, peoples r china. [li, shujun; yang, rui; tao, xiaojie] chinese acad sci, inst met res, shenyang natl lab mat sci, shenyang 110016, peoples r china. [jiang, xiaohong] shenyang hosp stomatol, dept orthodont, shenyang 110002, peoples r china.;liu, hc (reprint author), gen hosp chinese peoples liberat army, inst dent, beijing 100853, peoples r china;uhch301@sina.com
关键词	Titanium Alloy Micro-arc Oxidation Alkali Heatment Mc3t3-e1 Cells In Vitro Cell Response Apatite-forming Ability Surface Modification Titanium Surfaces Cell-attachment Ti Implants Metal Roughness Films Water
URL	查看原文
WOS记录号	WOS:000290592200005
引用统计	被引频次：25[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/30374
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	X. Han,H. C. Liu,D. S. Wang,et al. In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment[J]. Journal of Materials Science & Technology,2011,27(4):317-324.
APA	X. Han.,H. C. Liu.,D. S. Wang.,S. J. Li.,R. Yang.,...&X. H. Jiang.(2011).In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment.Journal of Materials Science & Technology,27(4),317-324.
MLA	X. Han,et al."In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment".Journal of Materials Science & Technology 27.4(2011):317-324.