Upconversion nanoparticles: synthesis, surface modification and biological applications

IMR OpenIR

	Upconversion nanoparticles: synthesis, surface modification and biological applications
	M. Wang; G. Abbineni; A. Clevenger; C. B. Mao; S. K. Xu
	2011
发表期刊	Nanomedicine-Nanotechnology Biology and Medicine
ISSN	1549-9634
卷号	7 期号:6 页码:710-729
摘要	New generation fluorophores, also termed upconversion nanoparticles (UCNPs), have the ability to convert near infrared radiations with lower energy into visible radiations with higher energy via a nonlinear optical process. Recently, these UCNPs have evolved as alternative fluorescent labels to traditional fluorophores, showing great potential for imaging and biodetection assays in both in vitro and in vivo applications. UCNPs exhibit unique luminescent properties, including high penetration depth into tissues, low background signals, large Stokes shifts, sharp emission bands, and high resistance to photobleaching, making UCNPs an attractive alternative source for overcoming current limitations in traditional fluorescent probes. In this article, we discuss the recent progress in the synthesis and surface modification of rare-earth doped UCNPs with a specific focus on their biological applications. From the Clinical Editor: Upconversion nanoparticles - a new generation of fluorophores - convert near infrared radiations into visible radiations via a nonlinear optical process. These UCNPs have evolved as alternative fluorescent labels with great potential for imaging and biodetection assays in both in vitro and in vivo applications. (C) 2011 Elsevier Inc. All rights reserved.
部门归属	[wang, meng; xu, shukun] northeastern univ, coll sci, shenyang 110819, peoples r china. [abbineni, gopal; clevenger, april; mao, chuanbin] univ oklahoma, dept chem & biochem, norman, ok 73019 usa. [wang, meng] chinese acad sci, inst met res, shenyang natl lab mat sci, shenyang, peoples r china.;xu, sk (reprint author), northeastern univ, coll sci, shenyang 110819, peoples r china;xushukun46@126.com
关键词	Upconversion Rare Earth Luminescent Materials Nanomaterials Biological Detection Doped Nayf4 Nanocrystals Infrared Quantum Counters In-vivo Monodisperse Nanocrystals Yb3++ Nanocrystals Hexagonal-phase Trifluoroacetate Precursors Upconverting Nanophosphors Fluorescent Nanocrystals Luminescent Properties
URL	查看原文
WOS记录号	WOS:000297699900008
引用统计	被引频次：432[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/30732
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	M. Wang,G. Abbineni,A. Clevenger,et al. Upconversion nanoparticles: synthesis, surface modification and biological applications[J]. Nanomedicine-Nanotechnology Biology and Medicine,2011,7(6):710-729.
APA	M. Wang,G. Abbineni,A. Clevenger,C. B. Mao,&S. K. Xu.(2011).Upconversion nanoparticles: synthesis, surface modification and biological applications.Nanomedicine-Nanotechnology Biology and Medicine,7(6),710-729.
MLA	M. Wang,et al."Upconversion nanoparticles: synthesis, surface modification and biological applications".Nanomedicine-Nanotechnology Biology and Medicine 7.6(2011):710-729.