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Dynamic behaviors of a Ca-P coated AZ31B magnesium alloy during in vitro and in vivo degradations
Q. Wang; L. L. Tan; W. L. Xu; B. C. Zhang; K. Yang
2011
发表期刊Materials Science and Engineering B-Advanced Functional Solid-State Materials
ISSN0921-5107
卷号176期号:20页码:1718-1726
摘要Surface modification can be an effective way to control the biodegradation behavior of magnesium alloys and even improve their biological properties. Much attention has been paid to the initial protection ability and biological properties of magnesium alloys coating. In this work, the dynamic behaviors of a Ca-P coated AZ31B magnesium alloy during the degradations in vitro and in vivo, including hemolysis, mechanical loading capability and implantation in animals, were investigated. The hemolytic rates of the alloy with and without coating were all declined to be lower than 5% after more than 20 days immersion in PBS. though an increase happened to the alloy at the early immersion of 3-7 days. Reduction of the mechanical loading capacity was gradually evolved for the coated alloy and the peak load retention of 85% was still maintained after 120 days degradation. The in vivo implantation indicated that the Ca-P coated AZ31B alloy showed a more suitable time dependent degradation behavior which was favorable for growth of the new tissue and the healing dynamics of bones, making it a promising choice for medical application. (C) 2011 Elsevier B.V. All rights reserved.
部门归属[wang, qiang; tan, lili; xu, wenli; zhang, bingchun; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china.;yang, k (reprint author), chinese acad sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china;lltan@imr.ac.cn kyang@imr.ac.cn
关键词Magnesium Alloy Ca-p Coating Degradation Hemolysis Implantation Calcium-phosphate Corrosion Behavior Zn Alloy Mg Precipitation Hemolysis Az91d
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WOS记录号WOS:000297877300016
引用统计
被引频次:50[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.imr.ac.cn/handle/321006/30734
专题中国科学院金属研究所
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GB/T 7714
Q. Wang,L. L. Tan,W. L. Xu,et al. Dynamic behaviors of a Ca-P coated AZ31B magnesium alloy during in vitro and in vivo degradations[J]. Materials Science and Engineering B-Advanced Functional Solid-State Materials,2011,176(20):1718-1726.
APA Q. Wang,L. L. Tan,W. L. Xu,B. C. Zhang,&K. Yang.(2011).Dynamic behaviors of a Ca-P coated AZ31B magnesium alloy during in vitro and in vivo degradations.Materials Science and Engineering B-Advanced Functional Solid-State Materials,176(20),1718-1726.
MLA Q. Wang,et al."Dynamic behaviors of a Ca-P coated AZ31B magnesium alloy during in vitro and in vivo degradations".Materials Science and Engineering B-Advanced Functional Solid-State Materials 176.20(2011):1718-1726.
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