Monte Carlo Simulation Study on Scaling Behavior in Growth of Antibody-antigen Complexes

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	Monte Carlo Simulation Study on Scaling Behavior in Growth of Antibody-antigen Complexes
	H. J. Wang; P. Zhang; X. W. Ba
	2010
发表期刊	Chemical Journal of Chinese Universities-Chinese
ISSN	0251-0790
卷号	31 期号:5 页码:1045-1050
摘要	The scaling behavior concerning the growth of antibody-antigen complexes was studied by the method of Monte Carlo simulation. The validity of the algorithm we used is demonstrated by the excellent agreement between analytical results and those of Monte Carlo simulation under the case of equal reactivity. For both cases of equal and unequal reactivities, the scaling exponents of the size distribution, the weight-average binding degrees, and the characteristic correlation length are obtained, and then the scaling law on the sol-gel transition is checked. It is shown that the effects of unequal reactivity on the growth of antibody-antigen complexes are significant, and this can provide some useful information for the clinic analysis of immunoreactions.
部门归属	[wang hai-jun; zhang ping; ba xin-wu] hebei univ, coll chem & environm sci, baoding 071002, peoples r china. [zhang ping] chengde med coll, inst biomed engn, chengde 067000, peoples r china. [wang hai-jun; ba xin-wu] hebei univ, minist educ, key lab med chem & mol diag, baoding 071002, peoples r china. [wang hai-jun; zhang ping; ba xin-wu] chinese acad sci, int ctr mat phys, shenyang 110016, peoples r china.;wang, hj (reprint author), hebei univ, coll chem & environm sci, baoding 071002, peoples r china;whj@mail.hbu.cn
关键词	Antibody-antigen Complex Scaling Behavior Sol-gel Phase Transition Monte Carlo Simulation Randomly Branched Polymers Average Molecular-weights Probability-theory Immune-complexes Viscoelasticity Aggregation Evolution Binding Ligands Size
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WOS记录号	WOS:000278159700036
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/31496
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	H. J. Wang,P. Zhang,X. W. Ba. Monte Carlo Simulation Study on Scaling Behavior in Growth of Antibody-antigen Complexes[J]. Chemical Journal of Chinese Universities-Chinese,2010,31(5):1045-1050.
APA	H. J. Wang,P. Zhang,&X. W. Ba.(2010).Monte Carlo Simulation Study on Scaling Behavior in Growth of Antibody-antigen Complexes.Chemical Journal of Chinese Universities-Chinese,31(5),1045-1050.
MLA	H. J. Wang,et al."Monte Carlo Simulation Study on Scaling Behavior in Growth of Antibody-antigen Complexes".Chemical Journal of Chinese Universities-Chinese 31.5(2010):1045-1050.