| Monte Carlo Simulation on Growth of Antibody-Antigen Complexes: the Role of Unequal Reactivity |
| P. Zhang; H. J. Wang
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| 2010
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| 发表期刊 | Chinese Physics Letters
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| ISSN | 0256-307X
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| 卷号 | 27期号:3 |
| 摘要 | Growth of Antibody-Antigen complexes in a multivalent Antibody-Antigen system is studied by the Monte Carlo simulation method. The validity of the algorithm is first demonstrated for the case of the equal reactivity, then the simulation is presented for the case of unequal reactivity. It is shown that the influence of the unequal reactivity on the critical point, size distribution and the weight-average binding degree is significant. Especially, the gelation regions for the cases of unequal reactivity are studied, which can provide some useful clues for the immunological experiments. |
| 部门归属 | [zhang ping; wang hai-jun] hebei univ, coll chem & environm sci, baoding 071002, peoples r china. [zhang ping] chengde med coll, dept biomed engn, chengde 067000, peoples r china. [wang hai-jun] chinese acad sci, int ctr mat phys, shenyang 110016, peoples r china. [wang hai-jun] hebei univ, key lab med chem & mol diag, minist educ, baoding 071002, peoples r china.;zhang, p (reprint author), hebei univ, coll chem & environm sci, baoding 071002, peoples r china;whj@mail.hbu.edu.cn
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| 关键词 | Molecular-weight Distribution
Soluble Immune-complexes
Condensation
Polymerization
Probability-theory
Size
Distributions
Aggregation
Evolution
Gelation
Ligands
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| URL | 查看原文
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| WOS记录号 | WOS:000275376200085
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| 引用统计 |
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| 文献类型 | 期刊论文
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| 条目标识符 | http://ir.imr.ac.cn/handle/321006/31715
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| 专题 | 中国科学院金属研究所
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推荐引用方式
GB/T 7714 |
P. Zhang,H. J. Wang. Monte Carlo Simulation on Growth of Antibody-Antigen Complexes: the Role of Unequal Reactivity[J]. Chinese Physics Letters,2010,27(3).
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| APA |
P. Zhang,&H. J. Wang.(2010).Monte Carlo Simulation on Growth of Antibody-Antigen Complexes: the Role of Unequal Reactivity.Chinese Physics Letters,27(3).
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| MLA |
P. Zhang,et al."Monte Carlo Simulation on Growth of Antibody-Antigen Complexes: the Role of Unequal Reactivity".Chinese Physics Letters 27.3(2010).
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