Study on beta-TCP Coated Porous Mg as a Bone Tissue Engineering Scaffold Material

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	Study on beta-TCP Coated Porous Mg as a Bone Tissue Engineering Scaffold Material
	F. Geng; L. L. Tan; B. C. Zhang; C. F. Wu; Y. L. He; J. Y. Yang; K. Yang
	2009
发表期刊	Journal of Materials Science & Technology
ISSN	1005-0302
卷号	25 期号:1 页码:123-129
摘要	Three-dimensional honeycomb-structured magnesium (Mg) scaffolds with interconnected pores of accurately controlled pore size and porosity were fabricated by laser perforation technique. Biodegradable and bioactive beta-tricalcium phosphate (beta-TCP) coatings were prepared on the porous Mg to further improve its biocompatibility, and the biodegradation mechanism was simply evaluated in vitro. It was found that the mechanical properties of this type of porous Mg significantly depended on its porosity. Elastic modulus and compressive strength similar to human bones could be obtained for the porous Mg with porosity of 42.6%-51%. It was observed that the human osteosarcoma cells (UMR106) were well adhered and proliferated on the surface of the beta-TCP coated porous Mg, which indicates that the beta-TCP coated porous Mg is promising to be a bone tissue engineering scaffold material.
部门归属	[geng, fang; tan, lili; zhang, bingchun; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. [geng, fang] chinese acad sci, grad sch, beijing 100049, peoples r china. [wu, chunfu; he, yonglian; yang, jiangyu] shenyang pharmaceut univ, dept pharmacol, shenyang 110016, peoples r china.;yang, k (reprint author), chinese acad sci, inst met res, shenyang 110016, peoples r china;kyang@imr.ac.cn
关键词	Magnesium Bone Tissue Engineering Beta-tcp Coating Biocompatibility Simulated Body-fluid Mechanical-properties Cancellous Bone Foam Scaffolds Magnesium Hydroxyapatite Porosity Bioceramics Fabrication Ph
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WOS记录号	WOS:000263620900019
引用统计	被引频次：60[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/31931
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	F. Geng,L. L. Tan,B. C. Zhang,et al. Study on beta-TCP Coated Porous Mg as a Bone Tissue Engineering Scaffold Material[J]. Journal of Materials Science & Technology,2009,25(1):123-129.
APA	F. Geng.,L. L. Tan.,B. C. Zhang.,C. F. Wu.,Y. L. He.,...&K. Yang.(2009).Study on beta-TCP Coated Porous Mg as a Bone Tissue Engineering Scaffold Material.Journal of Materials Science & Technology,25(1),123-129.
MLA	F. Geng,et al."Study on beta-TCP Coated Porous Mg as a Bone Tissue Engineering Scaffold Material".Journal of Materials Science & Technology 25.1(2009):123-129.