Synthesis of Magnetic Nanobiomaterials and Its Biological Effects

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	Synthesis of Magnetic Nanobiomaterials and Its Biological Effects
	X. F. Pang; B. Deng; Q. Zhao
	2009
发表期刊	Journal of Nanoscience and Nanotechnology
ISSN	1533-4880
卷号	9 期号:2 页码:1369-1373
摘要	Iron oxides and its hydrate nanoparticles, for example, nanoFe(3)O(4) and nanoFe(3)O(4) with hydroxyl, were synthesized by hydrothermal method, their sizes and features are evaluated by infrared spectra and Scanning Electron Microscope (SEM) etc. The dimensions of these nanoparticles produced are about 50-120 nm. In the investigation of influence of nanoFe(3)O(4) and nanoFe(3)O(4) with hydroxyl on crystalline states of amino acid molecules, their crystalline forms are different to that of pure amino acid molecules. The positions and widths of peaks of these nanoparticles in the infrared spectra of absorption are changed largely relative to that of pure amino acid molecules. From the experiments of microscope observation and infrared spectra of re-crytalline amino acids we see that the nanoFe(3)O(4) and nanoFe(3)O(4) with hydroxyl can change the structure of amino acid molecules. To study the toxicity of synthesized nanoparticles, the MTT (3-(4,5-dimethyl-thiazol 2-yl)-2,5 diphenyltetrazolium bromide) assay was used. The OD value (Optical Density) was used to calculated RGR (Relative Generation Rate) of cells, which determined the grade of cytotoxicity. The RGR of nanoparticles of iron oxide and its hydrate are about 1 to 2, which indicate that they have a lower toxicity.
部门归属	[pang xiao-feng; deng bo; zhao qiang] univ elect sci & technol china, inst life sci & technol, chengdu 610054, peoples r china. [pang xiao-feng] chinese acad sci, int ctr mat phys, shenyuning 110015, peoples r china.;pang, xf (reprint author), univ elect sci & technol china, inst life sci & technol, chengdu 610054, peoples r china
关键词	Magnetic Bio-nanomaterial Infrared Spectrum Cell Proliferation Biological Effect Synthesis
URL	查看原文
WOS记录号	WOS:000263653300159
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/32230
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	X. F. Pang,B. Deng,Q. Zhao. Synthesis of Magnetic Nanobiomaterials and Its Biological Effects[J]. Journal of Nanoscience and Nanotechnology,2009,9(2):1369-1373.
APA	X. F. Pang,B. Deng,&Q. Zhao.(2009).Synthesis of Magnetic Nanobiomaterials and Its Biological Effects.Journal of Nanoscience and Nanotechnology,9(2),1369-1373.
MLA	X. F. Pang,et al."Synthesis of Magnetic Nanobiomaterials and Its Biological Effects".Journal of Nanoscience and Nanotechnology 9.2(2009):1369-1373.